Metaphylaxis in patients with gout, complicated by urolithiasis and nephropathy
- Authors: Avdoshyn V.P1, Andryukhin M.I1, Annenkov A.V1, Pulbere S.A1, Chugayev V.V1
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- Issue: No 2 (2013)
- Pages: 30-33
- Section: Articles
- URL: https://journals.eco-vector.com/2075-3594/article/view/261733
- ID: 261733
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Abstract
Aim. Estimation of clinical efficacy of metaphylaxis in patients with gout, urate nephrolithiasis and nephropathy. Methods. 112 (79 men, 33 women, mean age 57+7 years) with gout, urate nephrolithiasis and nephropathy were included into the study. All of them were treated with Trometamol n (500 ml intravenously, course of 10 infusions). Duration of gout varied from 2 to 27 years (mean і0,2 years). Results. Use of Trometamol N was associated with decrease of uricemia, creatininemia and increase of urinary uric acid excretion. Gout arthritis attack was seen in only 1 (0,9%) of patients. Trometamol N was well tolerated. Conclusion. Trometamol N can be used for uricemia control in patients with gout and uric acid nephropathy.
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About the authors
V. P Avdoshyn
Email: susya@kmail.ru
M. I Andryukhin
A. V Annenkov
S. A Pulbere
V. V Chugayev
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