Nephrolithyasis a sign of idopathic hypercalciuria in children -inhabitants of Barnaul City


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Aim. Assessment of clinical and laboratory signs of nephrolithiasis in children - inhabitants of Barnaul City with determination of idiopathic hypercalciuria prevalence. Methods. 44 chidlren (age 1 month - 16 years, mean - 7,6+0,7 years) with nephrolithiasis, diagnosed in year 2011 - 20і3, were included into the study. Herditary anamnesis, clinical signs, blood biochemical parameters were analyzed. Results. Nephrolithiasis presence in close relatives was found in 47,7% of children. 68,2% of childrenuriurinary tract abnormalities 50,0% - urinary tract infections. Most prevalent clinical signs were disuria (34,4%) and pain (31,9%), most prevalent laboratory signs - hematuria, leucocyturia and cristalluria. Indiopathic hypercalciuria was found in 34 (77%) of children with nephrolithiasis. Conclusion. Idiopathic hypercalciuria is prevalent in children with nephrolithiasis.

Full Text

Restricted Access

References

  1. Зверев Я.Ф., Брюханов В.М., Лампатов В.В. и др. Современные представления о роли физико-химических факторов в патогенезе кальциевого нефролитиаза // Нефрология. - 2009. - № 13(1). - С. 39-50.
  2. Stamatelou K.K., Francis M.E., Jones C.A. et al. Time trends in reported prevalence of kidney stones in the United States: 1976-1994// Kidney Int. - 2003. - Vol. 63. - P. 1817-1823.
  3. Lieske J.C., Pena de la Vega L.S., Slezak J.M. et al. Renal stone epidemiology in Rochester, Minnesota: an update // Kidney Int. - 2006. - Vol. 69. - P. 760-764.
  4. Sakhaee K. Recent advances in the pathophysiology of nephrolithiasis // Kidney Int. - 2009. - Vol. 75(6). - P. 585-595.
  5. Scales C.D., Smith A.C., Hanley J.M. et al. Prevalence of kidney stones in the United States// Eur Urol. - 2012. - Vol. 62. - P. 160-165.
  6. Copelovitch L. Urolithiasis in children // Pediatr Clin North Am. - 2012. - Vol. 59(4). - P. 881-896.
  7. Van Dervoort K., Wiesen J., Frank R. et al. Urolithiasis in pediatric patients: a single center study of incidence, clinical presentation and outcome // J Urol. - 2007. - Vol. 177(6). - P. 2300-2305.
  8. Palmer J.S., Donaher E.R., Oriordan M.A. Diagnosis of pediatric patients: role of ultrasound and computerized tomography // J Urol. - 2005. - Vol. 174. - P. 1413-1416.
  9. Evans K, Costabile R.A. Time to development of symptomatic urinary calculi in a high risk environment// J Urol. - 2005. - Vol. 173. - P. 858-861.
  10. Brikowski T.H., Lotan Y., Pearle M.S. Climate-related increase in the prevalence of urolithiasis in the United State // Proc Natl Acad Sci U S A. - 2008. - Vol. 105. - P. 9841-9846.
  11. Nouvenne A., Meschi T., Prati A. et al. Effects of a low-salt diet on idiopathic hypercalciuria in calcium-oxalate stone formers: a 3-mo randomized controlled trial // Am J Clin Nutr. - 2010. - Vol. 91(3). - P. 565-570.
  12. Doglio E., Vezzoli G., Nouvenne A. et al. Nutrition in calcium nephrolithiasis // J Transi Med. - 2013. - 11:109. Published online 2013 May 1. doi: 10.1186/1479-5876-11-109.
  13. Bak M., Ural R., Agin H. et al. The metabolic etiology of urolitiasis in Turcish children // Int. Urol. Nephrol. - 2009. - Vol. 41. - P. 453-460.
  14. Spivacow F.R., Negri A.Z., del Valle E.E. et al. Metabolic risk factors in children with kidney stone disease // Pediatr. Nephrol. - 2008. - Vol. 23. - P. 1129-1133.
  15. Длин В.В., Османов И.М., Новиков В.П. и др. Дизметаболическая нефропатия, мочекаменная болезнь и нефролитиаз у детей. - М.: Оверлей. - 2005. - 232 с.
  16. Edvardsson V., Elidottir H., Indridason O. et al. High incidence of kidney stones in Icelandic children // Pediatr. Nephrol. - 2005. - Vol. 20. - P. 940-944.
  17. Milliner D.S., Murphy M.E. Urolithiasis in pediatric patients //Mayo Clin Proc. - 1993. - Vol. 68(3). - P. 241-248.
  18. Polito C., La Manna A., Nappi B. et al. Idiopathic hypercalciuria and hyperuricosuria: family prevalence of nephrolithiasis // Pediatr Nephrol. - 2000. - Vol. 14(12). - P. 1102-1104.
  19. Ertan P., Tekin J., Oger N. et al. Metabolic and demographic characteristics of children with urolitiasis in Western Turkey // Urol. Res. - 2011. - Vol. 39. - P. 105-110.
  20. Penido M.G.M.G., Diniz J.S.S., Moreira M.L.S.F. et al. Idiopathic hypercalciuria: presentation of 471 cases // J Pediatr (Rio J). - 2001. - Vol. 77(2). - P. 101-104.
  21. Lau K.K. Clinical manifestations of pediatric idiopathic hypercalciuria //Front Biosci (Elite Ed). - 2009. - Vol. 1. - P. 52-59.
  22. Srivastava T., Schwaderer A. Diagnosis and management of hypercalciuria in children // Curr Opin Pediatr. - 2009. - Vol. 21(2). - P. 214-219.
  23. Alon U.S., Zimmerman H., Alon M. Evaluation and treatment of pediatric idiopatic urolitiasis-revisited // Pediatr. Nephrol. - 2004. - Vol. 19. - P. 516-520

Supplementary files

Supplementary Files
Action
1. JATS XML

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies