Combined positron-emission tomographyand computed tomography scanning of the kidneys and urinary tract


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Abstract

Background. Combined positron-emission tomography and computed tomography (PET/СТ) allows to investigate the functional state of organs and systems in real time in vivo. The basis of the method includes the principle of incorporation of an isotope of vital biomolecules into the structure of actively multiplying or vigorously functioning cells. Objective. Evaluation of the possibility of analyzing the structural and functional state of the kidneys and urinary tract according to the results of РЕТ/СТ whole body scanning of patients with skin melanoma and prostate cancer without signs of metastasis and the presence of neuro-urological anamnesis. Material and methods. a retrospective analysis of 1ОО РЕТ/СТ findings of patients in these groups was carried out. In 50 cases, the scanning was conducted with the choline С ii, and in 50 cases - with the fludeoxyglucose F 18. РЕТ/СТ was performed by the standard method on a РЕТ/СТ scanner (Siemens Biograph, Germany) to assess the possible prevalence of the disease. Results. The obtained data allowed to conclude that РЕТ/СТ imaging of functionally consistent kidneys and urinary tract is possible and rather highly informative. Mathematical calculation of the intensity of radiopharmaceutical agent incorporation into the renal cortex, renal medulla, as well as the renal pelvis, makes it possible to evaluate the functional state of the renal parenchyma in the process of urine formation and urinary tract in the process of urine transport, and also to perform it separately for each organ. Conclusion. Structural and functional changes in the parenchyma of the kidneys and the upper urinary tract during the formation and transportation of urine can be visually and mathematically analyzed using the combined РЕТ/СТ method.

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About the authors

V. B Berdichevsky

Tyumen State Medical University

Email: neurourofcn@mail.ru
Doctor of Medical Sciences, Associate Professor at the Department of Oncology with a Course of Urology

B. A Berdichevsky

Tyumen State Medical University

Doctor of Medical Sciences, Professor at the Department of Oncology with a Course of Urology

V. A Zhmurov

Tyumen State Medical University

Doctor of Medical Sciences, Professor, Head of the Clinical Department of Propedeutics of Internal Diseases

D. A Barashin

Radiological Center of the Tyumen Regional Oncology Dispensary (SAHCITR MDCMC Medical City, Tyumen); Tyumen State Medical University of the Ministry of Health of the Russian Federation

External Doctorate Student at the Clinical Department of Propaedeutics of Internal Diseases; Radiologist

F. R Rasulov

Tyumen State Medical University

External Doctorate Student at the Clinical Department of Propedeutics of Internal Diseases

A. V Romanova

Tyumen State Medical University

Medical Resident at the Clinical Department of Internal Medicine Propedeutics

I. V Pavlova

Tyumen State Medical University

External Doctorate Student at the Clinical Department of Propedeutics of Internal Diseases

E. V Zagorchik

Tyumen State Medical University

6th-year Student of the Medical Faculty

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