ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment

Abstract

Перитонит является серьезным осложнением перитонеального диализа (ПД), и его профилактика и лечение имеют большое значение в снижении заболеваемости и смертности пациентов. в обновленных рекомендациях ISPD 2022 года пересмотрены и уточнены определения следующих понятий: рефрактерный перитонит, рецидивирующий перитонит, удаление катетера, связанное с перитонитом, перевод на гемодиализ, связанный с перитонитом, смерть, обусловленная перитонитом, и госпитализация, связанная с перитонитом. Определены новые категории перитонита и исходы, включая пре-перитонит, кишечный перитонит, катетер-ассоциированный перитонит и излеченный перитонит. Новые целевые показатели, рекомендованные для общей частоты заболеваемости перитонитом, должны составлять не более 0,40 эпизода в год с учетом риска, а процент пациентов, не заболевших перитонитом в единицу времени, должен составлять >80% в год. Также включены пересмотренные рекомендации по управлению контаминацией систем для ПД, антибиотикопрофилактике для инвазивных процедур, обучению и оценке ПД. Выделены новые рекомендации по управлению модифицируемыми факторами риска перитонита, такими как домашние животные, гипокалиемия и блокаторы Н2-гистаминовых рецепторов. Обновлены рекомендации по эмпирическому выбору антибиотиков и дозировке антибиотиков, по выбору стратегии лечения перитонита, вызванного специфическими микроорганизмами, также даны новые рекомендации по дополнительной пероральной терапии N-ацетилцистеином для смягчения ототоксичности аминогликозидов. Предложены новые направления для будущих исследований в области профилактики и лечения перитонита, связанного с ПД.

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Supplementary files

Supplementary Files
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