Gender differences in kidney function in COVID-19

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Abstract

Objective. Identification of gender differences in the kidney function in patients with COVID-19.

Material and methods. The study included 504 patients who were treated for the diagnosis of «Novel coronavirus infection caused by the SARS-CoV-2 virus». Patients were divided into two groups by gender: group A – 311 women, the mean age was 63.1±15.3 years, body mass index (BMI) – 28.8±6.1 kg/m2; group B – 193 men, the mean age was 58.3±15.9 years, BMI – 27.8±5.8 kg/m2. Blood serum creatinine levels were determined, the glomerular filtration rate (GFR) was calculated.

Results. On admission, 68.8% of women and 53.8% of men had signs of renal dysfunction, since the GFR was reduced; by the 7th day, renal function had not returned to normal in 33.6% of women and 43.1% of men, since the GFR remained reduced.

Conclusion. The course of COVID-19 has gender differences, which must be taken into account in clinical practice.

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About the authors

Svetlana A. Perepelitsa

Imannuel Kant Baltic Federal University

Author for correspondence.
Email: sveta_perepeliza@mail.ru
ORCID iD: 0000-0002-4535-9805

Dr. Sci. (Med.), Head of the Department of Surgical Disciplines of the Educational Scientific Cluster «Institute of Medicine and Life Sciences»

Russian Federation, 14 A.Nevsky str., Kaliningrad, 236041

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Supplementary files

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2. Fig. 1. Distribution of patients in groups depending on creatinine level on admission

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3. Fig. 2. Distribution of patients in groups according to the value of SCF

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4. Fig. 3. Dynamics of creatinine and glomerular filtration rate at the stages of treatment

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5. Fig. 4. SCF on the 7th day of treatment

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