Chronic pyelonephritis as a mimics of kidney tuberculosis

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Abstract

Background. The most common reason for late diagnosis of urogenital tuberculosis (UGTB) is low alertness of doctors; the second most common reason is the nature of the course of the disease, the absence of pathognomonic signs, the tendency to be mimics of other diseases.

Description of the clinical case. Patient E., 50 years old, complained of pain in the lumbar region and hypogastrium, periodic increases in body temperature to 37.5 ˚С, frequent urination, constant urine output through the vagina. Epidemiological history is burdened. The onset of the disease was at the age of 25, after which the patient repeatedly took courses of antibacterial treatment with little effect. Tuberculosis (TB) was diagnosed only at the age of 50, when kidney function ceased, cicatricial microcystis and vesicovaginal fistula formed.

Conclusion. The given example demonstrates errors in diagnosis. The long-term, recurrent nature of the inflammatory process against the background of repeated courses of antimicrobial therapy, aggravated contact with tuberculosis should have alerted the doctor to UGTB. Progressive decrease in bladder capacity also indicated a specific inflammation. A single negative PCR test for MBT is not a criterion for excluding TB. A decrease in the number of patients with kidney TB does not mean the disappearance of TB in this localization, but only indicates the difficulty of recognizing this disease.

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About the authors

Ekaterina V. Kulchavenya

Novosibirsk State Medical University; Avicenna Clinical Hospital

Author for correspondence.
Email: urotub@yandex.ru
ORCID iD: 0000-0001-8062-7775

Dr.Sci. (Med.), Professor, Department of Phthisiopulmonology, Scientific Director, Department of Urology

Russian Federation, Novosibirsk; Novosibirsk

Denis P. Kholtobin

Avicenna Clinical Hospital; Altai State Medical University

Email: urology-avicenna@mail.ru
ORCID iD: 0000-0001-6645-6455

Dr.Sci. (Med.), Professor, Department of Urology and Andrology with the Course of FPE, Head of the Department of Urology

Russian Federation, Novosibirsk; Barnaul

Sergey Yu. Shevchenko

City Hospital No. 3

Email: shevchenko_s@list.ru
ORCID iD: 0000-0001-5013-2667

Cand.Sci. (Med.), Deputy Chief Physician

Russian Federation, Novosibirsk

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Supplementary files

Supplementary Files
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1. JATS XML
2. Fig. 1. MSCT of the kidneys of patient E. Hydronephrosis, multiple cavities of the left kidney

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3. Fig. 2. Retrograde cystogram of patient E. Microcystis, vesicoureteral reflux on the right, vesicovaginal fistula (presence of contrast in the vagina)

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4. Fig. 3. Descending MSCT cystogram, 3D modeling. Microcystis, vesicovaginal fistula

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5. Fig. 4. Macroscopic specimen: left kidney of patient E. Multiple caverns filled with caseous masses

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6. Fig. 5. Macroscopic specimen: the bladder of patient E. is cicatricially deformed, reduced in size, the wall is sharply thickened, the cavity of the bladder is sharply narrowed, the mucous membrane is red with hemorrhages.

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7. Fig. 6. MSCT of the kidney with contrast, 3D modeling of patient E. Control 3 months after surgery

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