Prevalence of sarcopenia in patients with chronic heart failure and chronic kidney disease
- 作者: Sokolova A.V.1,2, Dragunov D.O.1,2, Arutyunov G.P.3
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隶属关系:
- Pirogov Russian National Research Medical
- Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department
- Pirogov Russian National Research Medical University
- 期: 卷 15, 编号 3 (2023)
- 页面: 18-23
- 栏目: Original Articles
- URL: https://journals.eco-vector.com/2075-3594/article/view/624720
- DOI: https://doi.org/10.18565/nephrology.2023.3.18-23
- ID: 624720
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详细
Objective. Evaluation of the prevalence of sarcopenia in patients with CKD and CHF.
Materials and methods. The analysis included 107 patients with an established diagnosis of CHF, mean age was 69.6±11.3 years. All patients underwent screening for sarcopenia and CKD in accordance with the recommendations. For statistical analysis of the obtained data, the R language and RStudio software were used.
Results. CKD was detected in 105 patients with CHF: 32 patients had C2, 31 patients had C3a, 32 patients had C3b, 4 patients had C4 (CKD4), and only 2 patients did not have CKD. The largest number of CHF decompensation was detected in patients with CKD3b and CKD4. Presarcopenia was detected in 39% of patients with CHF and CKD, and sarcopenia in 38%. According to multivariate regression analysis, the risk of sarcopenia was most influenced by fat mass OR 1.14, 95% CI [1.01;1.34], P=0.057, muscle mass index OR 0.61, 95% CI [0.42 ;0.79], P=0.002 and male gender OR 1.17, 95% CI [60.9;85.77], P<0.001.
Conclusion. In patients with CHF and CKD, the increase in sarcopenia occurs as the filtration function of the kidneys decreases.
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作者简介
Anna Sokolova
Pirogov Russian National Research Medical; Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department
编辑信件的主要联系方式.
Email: tamops2211@gmail.com
Cand.Sci. (Med.), Associate Professor, Associate Professor at the Department of Propaedeutics of Internal Diseases, Faculty of Pediatrics, Leading Specialist at the Organizational and Methodological Department for Therapy
俄罗斯联邦, 4 Startovaya st., Moscow; MoscowDmitry Dragunov
Pirogov Russian National Research Medical; Research Institute of Healthcare Organization and Medical Management of the Moscow Healthcare Department
Email: tamops2211@gmail.com
Cand.Sci. (Med.), Associate Professor, Associate Professor at the Department of Propaedeutics of Internal Diseases, Faculty of Pediatrics, Head of the Organizational and Methodological Department for Therapy
俄罗斯联邦, 4 Startovaya st., Moscow; MoscowGrigory Arutyunov
Pirogov Russian National Research Medical University
Email: tamops2211@gmail.com
Dr.Sci. (Med.), Professor, Corresponding Member of RAS, Head of the Department of Propaedeutics of Internal Diseases, Faculty of Pediatrics
俄罗斯联邦, 4 Startovaya st., Moscow参考
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