Application of the anolit in the prevention of peritoneal dialysis catheter-associated infections

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Objective. Evaluation of the effectiveness of the antiseptic drug Anolit neutral in the prevention of catheter exit site infection, tunnel infection and dialysis peritonitis.

Material and methods. A prospective study lasting 12 months based on the Peritoneal Dialysis Department of the City Clinical Hospital No. 52 of the Moscow Health Department. Of the 88 patients receiving outpatient peritoneal dialysis, 47 used Anolit neutral for hand and catheter exit site treatment, while another group of 41 patients used chlorhexidine bigluconate 0.05%.

Results. The incidence of catheter exit site infection did not differ in both groups. The incidence of dialysis peritonitis was generally less frequent in the Anolit neutral group compared to the chlorhexidine group, but was not statistically significant. The incidence of peritoneal dialysis catheter removal was similar in both groups. Skin erythema developed in only two patients using Anolit neutral.

Conclusion. The data obtained suggest that Anolit neutral may be used as an alternative to prevent catheter exit site infection, tunnel infection, and dialysis peritonitis.

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作者简介

Vitaly Berdinsky

Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department

编辑信件的主要联系方式.
Email: vitaly.berdinsky@yandex.ru
ORCID iD: 0000-0001-7407-5695

Head of the Nephrology Department No. 4

俄罗斯联邦, 3 Pekhotnaya St., Moscow, 123182

Oleg Kotenko

Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department; Pirogov Russian National Research Medical University

Email: olkotenko@yandex.ru
ORCID iD: 0000-0001-8264-7374

Dr.Sci. (Med.), Chief External Expert in Nephrology, Head, Professor at the Department of General Therapy, Faculty of Continuous Professional Education

俄罗斯联邦, 3 Pekhotnaya St., Moscow, 123182; Moscow

Nadiya Frolova

Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department; Russian University of Medicine

Email: nadiya.frolova@yandex.ru
ORCID iD: 0000-0002-6086-5220

Dr.Sci. (Med.), Deputy Chief Physician for Nephrology, Associate Professor at the Department of Nephrology, Faculty of Continuous Professional Education

俄罗斯联邦, 3 Pekhotnaya St., Moscow, 123182; Moscow

Irina Kargalskaya

Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department

Email: info@longavitapro.com
ORCID iD: 0009-0006-6261-0607

Head of the Telenephrology Center project, Head of the Patient-Oriented Telemedicine Committee at the All-Russian Union of Patients

俄罗斯联邦, 3 Pekhotnaya St., Moscow, 123182

Anzhela Ushakova

Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department

Email: anzhela_52@inbox.ru
ORCID iD: 0000-0002-3959-6281

Head of the Hemodialysis Departmen

俄罗斯联邦, 3 Pekhotnaya St., Moscow, 123182

Alena Orlova

Moscow City Scientific and Practical Center for Nephrology and Transplanted Kidney Pathology, City Clinical Hospital No. 52 of the Moscow Healthcare Department

Email: DOC.alena.orlova@mail.ru
ORCID iD: 0009-0000-5428-3649

Nephrologist, Hemodialysis Department

俄罗斯联邦, 3 Pekhotnaya St., Moscow, 123182

Igor Kozlov

OOO «Vitold Bakhir Institute of Electromechanical Systems and Technologies»

Email: ph.d.kiv@mail.ru

Cand.Sci. (Tech.), Chief Technologist

俄罗斯联邦, Bldg. 3, 34 Narodnogo Opolcheniya St., Moscow, 123423

Oleg Suvorov

Russian Biotechnology University (ROSBIOTECH)

Email: SuvorovOA@yandex.ru
ORCID iD: 0000-0003-2100-0918

Dr.Sci. (Tech.), Professor oatf the Department of Food Industry, Hotel Business and Service

俄罗斯联邦, 11 Volokolamskoe Shosse, Moscow, 125080

参考

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  2. Chow K.M., Li PK-T., Cho Y., et al. ISPD Catheter-related Infection Recommendations: 2023 Update. Peritoneal Dialysis International. 2023;43(3):201-219. doi: 10.1177/08968608231172740
  3. Tsai CC, Yang PS, Liu CL, Wu CJ, Hsu YC, Cheng SP. Comparison of topical mupirocin and gentamicin in the prevention of peritoneal dialysis-related infections: A systematic review and meta-analysis. Am J Surg. 2018 Jan;215(1):179-185. doi: 10.1016/j.amjsurg.2017.03.005. Epub 2017 Mar 15. PMID: 28341139.
  4. Cho Y., Johnson D.W. Peritoneal dialysis-related peritonitis: towards improving evidence, practices, and outcomes. Am J Kidney Dis. 2014;64(2):278-89. doi: 10.1053/j.ajkd.2014.02.025. Epub 2014 Apr 18. PMID: 24751170.
  5. Li P.K., Chow K.M., Cho Y., et al. ISPD peritonitis guideline recommendations: 2022 update on prevention and treatment. Perit Dial Int. 2022;42(2):110–153.
  6. Rigo M., Pecoits-Filho R., Lambie M., et al. Clinical utility of a traditional score system for the evaluation of the peritoneal dialysis exit-site infection in a national multicentric cohort study. Perit Dial Int. 2021;41(3):292–297.
  7. Schmitt R., Haller H., Hiss M. Quiz page September 2012: erythematous rash around peritoneal dialysis catheter exit site. Am J Kidney Dis. 2012;60(3):A29–A31.
  8. Schmitt R., Haller H., Hiss M. Quiz page September 2012: erythematous rash around peritoneal dialysis catheter exit site. Am J Kidney Dis. 2012;60(3):A29–A31.
  9. Twardowski Z.J., Prowant B.F. Classification of normal and diseased exit sites. Perit Dial Int. 1996;16(Suppl 3):S32–S50.
  10. Plum J., Sudkamp S. Grabensee B. Results of ultrasound-assisted diagnosis of tunnel infections in continuous ambulatory peritoneal dialysis. Am J Kidney Dis. 1994;23(1):99–104.

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