Analysis of demographic, clinical and laboratory parameters in COVID-19 patients with acute kidney injury

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Аннотация

Objective: Improvement of understanding of risk predictors of renal complications after COVID-19 in patients with and without diabetes mellitus (DM), which will allow developing effective prevention and treatment strategies.

Material and methods. The study included 386 patients who were divided into groups depending on the glomerular filtration rate (SFR) calculated using the CKD-EPI formula. Patients were classified as having normal renal function (≥90 ml/min/1.73 m2) and impaired renal function (≤89 ml/min/1.73 m2).

Results. Patients with impaired renal function were significantly older, had higher body mass index (BMI) and lung injury compared to patients with normal renal function. Patients with decreased GFR had hematological abnormalities, such as increased hematocrit and decreased lymphocyte count. These changes were especially pronounced in men and diabetic patients, indicating possible inflammatory and metabolic effects on kidney injury in these groups.

Conclusion. Older age, increased BMI and signigicant lung injury were significant predictors of renal injury in patients with COVID-19, especially in diabetic patients. Regular assessment of GFR and early management of inflammatory processes may be key to preventing renal complications in this category of patients.

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Авторлар туралы

Abduhalim Abdurakhimov

Andijan State Medical Institute

Хат алмасуға жауапты Автор.
Email: abduhalimaka@mail.ru
ORCID iD: 0000-0003-4541-0436

Teaching Assistant of the Department

Өзбекстан, Andijan

Әдебиет тізімі

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