Современные возможности применения фосфат-связывающих препаратов у больных, находящихся на диализе
- Авторы: Горелова Е.А1, Чернышева Н.Н1, Котенко О.Н2, Шутов Е.В1,3
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Учреждения:
- ГБУЗ «Городская клиническая больница им. С.П. Боткина»
- ГБУЗ «Городская клиническая больница № 52 ДЗМ»
- ГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» М3 РФ
- Выпуск: № 1 (2017)
- Страницы: 71-80
- Раздел: Статьи
- URL: https://journals.eco-vector.com/2075-3594/article/view/272764
- ID: 272764
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Е. А Горелова
ГБУЗ «Городская клиническая больница им. С.П. Боткина»
Email: gorelova.ea@mail.ru
врач-нефролог Москва
Н. Н Чернышева
ГБУЗ «Городская клиническая больница им. С.П. Боткина»врач-нефролог Москва
О. Н Котенко
ГБУЗ «Городская клиническая больница № 52 ДЗМ»
Email: info@gkb52.mosgorzdrav.ru
к.м.н., главный специалист по нефрологии ДЗМ, заместитель главного врача по нефрологической помощи Москва
Е. В Шутов
ГБУЗ «Городская клиническая больница им. С.П. Боткина»; ГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» М3 РФд.м.н., профессор кафедры нефрологии и гемодиализа; заведующий отделением диализа Москва
Список литературы
- Zhang Q.L., Rothenbacher D. Prevalence of chronic kidney disease in population-based studies: systematic review. BMC Public Health. 2008; 8: 117. doi: 10.1186/1471-2458-8-117.
- Couser W.G., Remuzzi G., Mendis S., Tonelli M. The contribution of chronic kidney disease to the global burden of major non-communicable diseases. Kidney Int. 2011; 80: 1258-1270. Doi: 10.1038/ ki.2011.368.
- Gonzalez-Parra E., Tunon J., Egido J., Ortiz A. Phosphate: a stealthier killer than previously thought? Cardiovas. Pathol. 2012; 21: 372-381. doi: 10.1016/j.carpath.2012.02.008.
- Kasiske B.L., Zeier M.G., Chapman J.R., et al.; Kidney disease: improving global outcomes. KDIGO clinical practice guideline for the care of kidney transplant recipients: a summary. Kidney Int. 2010; 77: 299-311. doi: 10.1038/ki.2009.377.
- Giachelli C.M. The emerging role of phosphate in vascular calcification. Kidney Int. 2009; 75: 890-897. doi: 10.1038/ki.2008.644.
- Block G.A. Screening dialysis patients for vascular calcification. Semin Dial. 2010; 23(3): 271-276. doi: 10.1111/j.1525-139X.2010.00727.x.
- Floege J., Kim J., Ireland E., et al.; ARO Investigators. Serum iPTH, calcium and phosphate, and the risk of mortality in a European haemodialysis population. Nephrol Dial. Transplant. 2011; 26: 1948-1955. doi: 10.1093/ndt/gfq219.
- Tentori F., Blayney M.J., Albert J.M., et al. Mortality riskfor dialysis patients with different levels of serum calcium, phosphorus, and PTH: the Dialysis Outcomes and Practice Patterns Study (DOPPS). Am. J. Kidney Dis. 2008; 52(3): 519-530. doi: 10.1053/j.ajkd.2008.03.020.
- Block G.A, Hulbert-Shearon T.E., Levin N.W., Port F.K. Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: a national study. Am. J. Kidney Dis. 1998; 31(4): 607-617.
- Block G.A, Klassen P.S., Lazarus J.M., et al. Mineral metabolism, mortality, and morbidity in maintenance hemodialysis. JASN. 2004; 15(8): 2208-2218.
- Slinin Y., Foley R.N., Collins A.J. Calcium, phosphorus, parathyroid hormone, and cardiovascular disease in hemodialysis patients: the USRDS waves 1, 3, and 4 study. JASN. 2005; 16(6): 1788-1793.
- Lopes A.A, Tong L., Thumma J., et al. Phosphate binder use and mortality among hemodialysis patients in the dialysis outcomes and practice patterns study (dopps): evaluation of possible confounding by nutritional status. Am. J. Kidney Dis. 2012; 60(1): 90-101. doi: 10.1053/j.ajkd.2011.12.025.
- Kidney Disease: Improving Global Outcomes. (KDIGO) CKD-MBD Work Group. KDIGO clinical practice guideline for the diagnosis, evaluation, prevention, and treatment of chronic kidney diseasemineral and bone disorder (CKD-MBD). Kidney Int. Suppl. 2009; 113: S1-S130. doi: 10.1038/ki.2009.188.
- National Kidney Foundation. K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. Am. J. Kidney Dis. 2003; 42: S1-S201.
- Noori N., Kalantar-Zadeh K., Kovesdy C.P., et al. Association of dietary phosphorus intake and phosphorus to protein ratio with mortality in hemodialysis patients. Clin. J. Am. Soc. Nephrol 2010; 5(4): 683-692. doi: 10.2215/CJN.08601209.
- Heng A.-E., Cano N.J.M. Nutritional problems in adult patients with stage 5 chronic kidney disease on dialysis (both haemodialysis and peritoneal dialysis). NDTPlus. 2010; 3: 109-117.
- Shinaberger C.S., Greenland S., Kopple J.D., et al. Is controlling phosphorus by decreasing dietary protein intake beneficial or harmful in persons with chronic kidney disease? Am. J. Clin. Nutr. 2008; 88: 1511-1518. doi: 10.3945/ajcn.2008.26665.
- Lynch K.E., Lynch R., Curhan G.C., Brunelli S.M. Prescribed dietary phosphate restriction and survival among hemodialysis patients. Clin. J. Am. Soc. Nephrol. 2011; 6: 620-629. doi: 10.2215/CJN.04620510.
- Ritz E., Hahn K., Ketteler M., et al. Phosphate additives in food - a health risk. Dtsch. Arztebl. Int. 2012; 109: 49-55.
- Uribarri J. Phosphorus homeostasis in normal health and in chronic kidney disease patients with special emphasis on dietary phosphorus intake. Semin. Dial. 2007; 20: 295-301.
- Penne E.L., van der Weerd N.C., van den Dorpel M.A., et al. Short-term effects of online hemodiafiltration on phosphate control: a result from the randomized controlled Convective Transport Study (CONTRAST). Am. J. Kidney Dis. 2010; 55: 77-87.
- Kuhlmann M.K. Phosphate elimination in modalities of hemodialysis and peritoneal dialysis. Blood Purif. 2010; 29: 137-144. doi: 10.1159/000245640.
- Suri R.S., Garg A.X., Chertow G.M., et al. Frequent Hemodialysis Network (FHN) randomized trials: study design. Kidney Int. 2007; 71(4): 349-359.
- Movilli E., Camerini C., Gaggia P., et al. Effect of post-dilutional on-line haemodiafiltration on serum calcium, phosphate and parathyroid hormone concentrations in uraemic patients. Nephrol Dial. Transpl. 2011; 26(12): 4032-4037. doi: 10.1093/ndt/gfr179.
- Martin K.J., Gonzalez E.A. Prevention and control of phosphate retention/hyperphosphatemia in CKD-MBD: what is normal, when to start, and how to treat? Clin. J. Am. Soc. Nephrol. 2011; 6(2): 440-446. doi: 10.2215/CJN.05130610.
- Locatelli F., Altieri P., Andrulli S., et al. Phosphate levels in patients treated with low-flux haemodialysis, pre-dilution haemofiltration and haemodiafiltration: post hoc analysis of a multicentre, randomized and controlled trial. Nephrol. Dial. Transplant. 2014; 29(6): 1239-1246. doi: 10.1093/ndt/gfu031.
- Kalantar-Zadeh K., Kuwae N., Regidor D.L., et al. Survival predictability of time-varying indicators of bone disease in maintenance hemodialysis patients. Kidney Int. 2006; 70(4): 771-780.
- Covic A., Kothawala P., Bernal M., et al. Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of all-cause mortality, cardiovascular mortality and cardiovascular events in chronic kidney disease. Nephrol. Dial. Transplant. 2009; 24(5): 1506-1523. doi: 10.1093/ndt/gfn613.
- Isakova T., Gutiérrez O.M., Chang Y., et al. Phosphorus binder and survival on hemodialysis. J. Am. Soc. Nephrol 2009; 20: 388-396. doi: 10.1681/ASN.2008060609.
- Cannata-Andia J.B. The use of phosphate binding agents is associated with lower mortalityresultsfrom the COSMOS study. 49th ERA-EDTA Congress, May 24-27, 2012. Paris, France.
- Kakuta T., Tanaka R., Hyodo T., et al. Effect of sevelamer and calcium-based phosphate binders on coronary artery calcification and accumulation of circulating advanced glycation end products in hemodialysis patients. Am. J. Kidney Dis. 2011; 57(3): 422-431. doi: 10.1053/j.ajkd.2010.10.055.
- Jamal S.A., Vandermeer B., Raggi P., et al. Effect of calcium-based versus non-calcium-based phosphate binders on mortality in patients with chronic kidney disease:an updated systematic review and metaanalysis. Lancet. 2013; 382: 1268-1277. doi: 10.1016/S0140-6736(13)60897-1.
- Chertow G.M., Burke S.K, Raggi P.; Goal Working Group. Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. Kidney Int. 2002; 62: 245-252.
- Block G.A, Spiegel D.M., Ehrlich J., et al. Effects of sevelamer and calcium on coronary artery calcification in patients new to hemodialysis. Kidney Int. 2005; 68: 1815-1824.
- Block G.A, Raggi P., Bellasi A, et al. Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients. Kidney Int. 2007; 71: 438-441.
- Spiegel D.M., Raggi P., Smits G., Block G.A. Factors associated with mortality in patients new to haemodialysis. Nephrol. Dial. Transplant. 2007; 22: 3568-3572.
- Renagel® [PrescribingInformation]. Cambridge: Genzyme Inc., 2014.
- Fosrenol® [Prescribing Information]. Wayne, PA Shire US Inc., 2014.
- Phoslyrd® [Prescribing Information]. Waltham, MA: Fresenius MedicaCare North America, 2011.
- Ренвелла®: инструкция по применению. URL: http://www.grls.rosminzdrav.ru
- Akizawa T., Origasa H., Kameoka C., et al.; Bixalomer Study Group. Randomized controlled trial of bixalomer versus sevelamer hydrochloride in hemodialysis patients with hyperphosphatemia. Ther. Apher. Dial. 2014;18:122-131. doi: 10.1111/1744-9987.12068.
- Вельфоро® 500: инструкция по применению. URL:http://www.grls.rosminzdrav.ru
- Auryxia® [Prescribing Information]. NY: Keryx Biopharmaceuticab, 2014.
- Daugirdas J.T., Finn W.F., Emmett M., Chertow G.M.; Frequent Hemo-dialysis Network Trial Group. The phosphate binder equivalent dose. Semin. Dial. 2011;24:41-49. doi: 10.1111/j.1525-139X.2011.00849.x.
- Daugirdas J.T., Chertow G.M., Larive B., et al.; Frequent Hemodialysis Network Trial Group. Effects of frequent hemodialysis on measures of CKD mineral and bone disorder. J. Am. Soc. Nephrol 2012;23:727-738. doi: 10.1681/ASN.2011070688.
- Daugirdas J.T., Blake P., Ing T. Bone disease. In: Handbook of dialysis. PA, 2015.
- Savica V., Bellinghieri G., Monardo P., et al. An update on calcium metabolism alterations and cardiovascular risk in patients with chronic kidney disease:questions, myths and facts. J. Nephrol. 2013; 26: 45-464. doi: 10.5301/jn.5000189.
- Spiegel D.M., Block G.A. Should we be using calcium-containing phosphate binder in patients on dialysis? Nat. Clin. Pract. Nephrol. 2008; 4: 118-119.
- Pflanz S., Henderson I.S., McElduff N., et al. Calcium acetate versus calcium carbonate as phosphate-binding agents in chronic haemodialysis. Nephrol. Dial. Transplant. 1994; 9: 1121-1124.
- Saif I., Halim A, Altaf A., et al. Comparison of calcium acetate with calcium carbonate as phosphate binder in patients on maintenance haemodialysis. J. Ayub. Med. Coll. Abbottabad. 2007; 19: 26-28.
- Choy B.Y., Lo W.K., Cheng I.K.P. Effectiveness of calcium acetate as a phosphate binder in patients undergoing continuous ambulatory peritoneal dialysis. Hong Kong Med. J. 1998; 4: 23-26.
- ОсваРен®: инструкция по применению. URL: http://www.grls.rosminzdrav.ru.
- de Francisco A.L., Leidig M., Covic A.C., et al. Evaluation of calcium acetate/magnesium carbonate as a phosphate binder compared with sevelamer hydrochloride in haemodialysis patients:a controlled randomized study (CALMAG study) assessing efficacy and tolerability. Nephrol. Dial. Transplant. 2010; 25(11): 3707-3717. doi: 10.1093/ndt/gfq292.
- Chertow G.M., Martin K.J. Current and future therapies for the medical management of secondary hyperparathyroidism. Semin. Dial. 1998; 11: 267-270.
- Slatopolsky E., Burke S.K., Dillon M.A. RenaGel, a nonabsorbed calcium- and aluminum-free phosphate binder lowers serum phosphorus and serum parathyroid hormone. The RenaGel Study Group. Kidney Int. 1999; 55: 299-307.
- Bleyer A.J., Burke S.K., Dillon M., et al. A comparison of the calcium-free phosphate binder sevelamer hydrochloride with calcium acetate in the treatment of hyperphosphatemia in hemodialysis patients. Am. J. Kidney Dis. 1999; 33(4): 694-701.
- Hutchison A.J., Speake M., Al-Baaj F. Reducing high phosphate levels in patients with chronic renal failure undergoing dialysis:a 4-week, dose-finding, open-label study with lanthanum carbonate. Nephrol Dial. Transplant. 2004;19:1902-1906.
- Finn W.F., Joy M.S., Hladik G.; Lanthanum Study Group. Efficacy and safety of lanthanum carbonate for reduction of serum phosphorus in patients with chronic renal failure receiving hemodialysis. Clin. Nephrol. 2004; 62: 193-201.
- Sprague S.M. A comparative review of the efficacy and safety of established phosphate binders: calcium, sevelamer, and lanthanum carbonate. Curr. Med. Res. Opin. 2007; 23: 3167-3175.
- Zhang C., Wen J., Li Z., Fan J. Efficacy and safety of lanthanum carbonate on chronic kidney disease-mineral and bone disorder in dialysis patients: a systematic review. BMC Nephrol. 2013; 4: 226. doi: 10.1186/1471-2369-14-226.
- D’Haese P.C., Spasovski G.B., Sikole A., et al. A multicenter study on the effects of lanthanum carbonate (Fosrenol) and calcium carbonate on renal bone disease in dialysis patients. Kidney Int. Suppl. 2003;63:S73.
- Malluche H.H., Siami G.A, Swanepoel C., et al.; SPD405-307 Lanthanum Carbonate Study Group. Improvements in renal osteodystrophy in patients treated with lanthanum carbonate for two years. Clin. Nephrol. 2008;70:284-295.
- Haratake J., Yasunaga C., Ootani A., et al. Peculiar histiocytic lesions with massive lanthanum deposition in dialysis patients treated with lanthanum carbonate. Am. J. Surg. Pathol. 2015; 39: 767-771. doi: 10.1097/PAS.0000000000000385.
- Wilhelm M., Gaillard S., Rakov V., Funk F. The iron-based phosphate binder PA21 has potent phosphate binding capacity and minimal iron release across a physiological pH range in vitro. Clin. Nephrol. 2014; 81: 251-258.
- Phan O., Maillard M., Funk F., et al. Effect of Pa21, a new ton-based phosphate binder on fibroblast growth factor 23 (Fgf23) and vascular calcification in uremic rats. J. Hypertens. 2015; 33(1): e16-e17. doi: 10.1097/01.hjh.0000467394.66592.05.
- Wuthrich R.P., Chonchol M., Covic A., et al. Randomized clinical trial of the ton-based phosphate binder PA21 in hemodialysis patients. Clin. J. Am. Soc. Nephrol. 2013; 8: 280-289. doi: 10.2215/CJN.08230811.
- Floege J., Covic A.C., Ketteler M., et al.; PA21 Study Group. A phase III study of the efficacy and safety of a novel ton-based phosphate binder in dialysis patients. Kidney Int. 2014; 86: 638-647. doi: 10.1038/ki.2014.58.
- Floege J., Covic A.C., Ketteler M., et al.; Sucroferric Oxyhydroxide Study Group. Long-term effects of iron-based phosphate binder, sucroferric oxyhydroxide, in dialysis patients. Nephrol. Dial. Transplant. 2015301037-1046. doi: 10.1093/ndt/gfv006.
- Parameswaran V., Ficociello L.H., Van Zandt C.R., et al. Pill Burden and Serum Phosphorus in Hemodialysis Patients Switched from Sevelamer to Sucroferric Oxyhydroxide. J.Am. Soc. Nephrol. 201627FR-PO 428.
- Sprague S.M., Covic A.C.,-Floege J., et al. Pharmacodynamic effects of sucroferric oxyhydroxide and sevelamer carbonate on vitamin d receptor agonist bioactivity in dialysis patients. Am. J. Nephrol. 2016;44:104-112. doi: 10.1159/000447600.
- Yaguchi A., Yonekubo S., Maruyama I., et al. Comparison of Phosphate Binding Capacities of PA21, a novel phosphate binder, with those of other phosphate binders in vitro and in vivo. Drug Res. 2016; 66(5): 262-269. doi: 10.1055/s-0035-1569328.
- Dwyer J.P., Sika M., Schulman G., et al.; Collaborative Study Group. Dose-response and efficacy of ferric citrate to treat hyperphosphatemia in hemodialysis patients:a short-term randomized trial. Am. J. Kidney Dis. 2013; 61: 759-766. doi: 10.1053/j.ajkd.2012.11.041.
- Van Buren P.N., Lewis J.B., Dwyer J.P., et al.; Collaborative Study Group. The phosphate binder ferric citrate and mineral metabolism and inflammatory markers in maintenance dialysis patients: results from prespecified analyses of a randomized clinical trial. Am. J. Kidney Dis. 2015; 66: 479-488. doi: 10.1053/j.ajkd.2015.03.013.
- Lewis J., Sika M., Koury M., et al.; Collaborative Study Group. Ferric citrate controls phosphorus and delivers iron in dialysis patients. J. Am. Soc. Nephrol. 2015; 26: 493-503. doi: 10.1681/ASN.2014020212.
- Cheng S.C., Young D.O., Huang Y., Delmez J.A., Coyne D.W. A randomized, double-blind, placebocontrolled tial of niacinamide for reduction of phos-phorus in hemodialysis patients. Clin. J. Am. Soc. Nephrol. 2008;3:1131-1138. doi: 10.2215/CJN.04211007.
- Block G.A, Persky M.S., Shamblin B.M., et al. Effect of salivary phosphate-binding chewinggum on serum phosphate in chronic kidney dis-ease. Nephron. Clin. Pract. 2013;123:93-101. doi: 10.1159/000351850.