New approaches in the diagnosis and treatment of CKD-MBD (KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD)


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In the summer of this year, revised kdigo clinical recommendations on mineral and bone disorders (MBD) in chronic kidney disease (CKD) were revised; they were previously adopted in 2009 (CKD-MBD-2009). The article discusses updates in more details. The changes that appeared in the updates (CKD-MBD-2017) concern several chapters: Chapter 3.2: "Diagnosis of CKD-MBD: Bones", Chapter 4.1. "Treatment of CKD-MBD targeted at lowering high serum phosphate and maintaining serum calcium", Chapter 4.2. "Treatment of abnormal PTH levels in CKD-MBD" (PTH - parathyroid hormone), Chapter 4.3. "Treatment of bone with bisphosphonates, other osteoporosis medications, and growth hormone", Chapter 5. "Evaluation and treatment of kidney transplant bone disease". Thus, the updates are related to the diagnosis of MBDs in CKD, the issues of phosphate-lowering therapy, therapy aimed at reducing PTH levels, and management of MBDs in patients with kidney transplant. Updates allow for the diagnosis and management of MBDs in CKD, taking into account modern views on this problem.

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作者简介

M. Batyushin

FSBEI HE "Rostov State Medical University” of the RMH

Email: nephr-roon@rambler.ru
Doctor of Medical Sciences, Head of the Department of Nephrology, Professor at the Department of Internal Diseases № 2

参考

  1. KDIGO Clinical Practice Guideline for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Kidney Int. 2009; 76(113): 1-130.
  2. KDIGO 2017 Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease -Mineral and Bone Disorder (CKD-MBD). Kidney Int. 2017; 7(1): 1-59.

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