Morphological structure of late kidney transplant dysfunction

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Objective: to analyze the causes of late kidney allograft dysfunction according to results of kidney transplant histopathological examination performed from 2013 to 2022.

Material and methods. Analysis of late kidney allograft dysfunction causes was carried out according to 431 reports of kidney transplant biopsies performed in Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology, Republic of Belarus.

Results. The main causes of kidney transplant dysfunction in late posttransplant period were antibody-mediated rejection – 26.7%, recurrent or de novo glomerular diseases – 22.7%, chronic allograft nephropathy – 16%.

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作者简介

Nadzeya Rapetskaya

Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology

编辑信件的主要联系方式.
Email: n.rapetskaja@gmail.com
ORCID iD: 0009-0005-4560-1162

Nephrologist, Department of Transplant Nephrology

白俄罗斯, Minsk, Semashko str., 8

Kirill Komissarov

Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology; Belarusian State Medical University

Email: kirill_ka@tut.by
ORCID iD: 0000-0002-2648-0642

PhD (Med. Sci), Associate Professor, Head of the Department of Nephrology, Renal Replacement Therapy and Kidney Transplantation

白俄罗斯, Minsk; Minsk, Semashko str., 8

Margarita Dmitrieva

Belarusian State Medical University

Email: mvdmitieva@inbox.ru
ORCID iD: 0000-0002-2958-9424

PhD (Med. Sci), Associate Professor, Department of Pathological Anatomy and Forensic Medicine

白俄罗斯, Minsk, Kizhevatova str., 60

Tatiana Liatkoyskaya

Belarusian State Medical University

Email: taletkovskaya@mail.ru
ORCID iD: 0000-0002-9381-2985

PhD (Med. Sci), Associate Professor, Head of the Department of Pathological Anatomy and Forensic Medicine

白俄罗斯, Minsk, Kizhevatova str., 60

Aleh Kalachyk

Minsk Scientific and Practical Center for Surgery, Transplantology and Hematology

Email: oleg_kalachik@hotmaill.com
ORCID iD: 0009-0002-6954-675X

DSc (Med. Sci), Professor, Deputy Director for Medical Affairs

白俄罗斯, Minsk, Semashko str., 8

参考

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2. Fig. 1. Algorithm for selecting kidney transplant biopsy reports performed at the State Institution “Minsk Scientific and Practical Center for Transplant Surgery and Hematology” from 2013 to 2022.

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3. Fig. 2. Morphological structure of causes of late renal graft dysfunction based on the results of renal graft biopsies performed at the State Institution "Minsk Scientific and Practical Center for Transplant Surgery and Hematology" from 2013 to 2022.

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4. Fig. 3. Structure of cellular renal graft rejection based on the results of renal graft biopsies performed at the State Institution "Minsk Scientific and Practical Center for Transplant Surgery and Hematology" from 2013 to 2022.

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5. Fig. 4. Impact of the duration of graft functioning on the structure of causes of renal allograft dysfunction based on the results of renal graft biopsies performed at the State Institution "Minsk Scientific and Practical Center for Transplant Surgery and Hematology" from 2013 to 2022.

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