Multifactorial kidney damage in a comorbid patient

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详细

Chronic kidney disease (CKD) is associated with severe comorbidity of a wide range of mental and physical conditions. The presence of concomitant pathologies aggravates the course of the underlying disease and contributes to the progression of kidney damage. The article presents a clinical description of a comorbid 80-year-old female patient with multifactorial renal damage due to arterial hypertension, viral hepatitis C, purine metabolism disorders, and markers of autoimmune damage based on the results of serological and intravital pathological examination. The mechanisms of complex renal damage and the importance of influencing them to maintain an optimal quality of life in a comorbid patient are discussed.

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作者简介

Valentina Yumasheva

Sechenov University

编辑信件的主要联系方式.
Email: valentina-jumasheva@rambler.ru
ORCID iD: 0000-0002-4388-5609

6th-Year Student, Sechenov University

白俄罗斯, Bldg. 2, 8 Trubetskaya St., Moscow, 119992

Irina Komarova

Sechenov University

Email: plaksuchka@rambler.ru
ORCID iD: 0000-0001-6425-0621

Cand.Sci. (Med.), Associate Professor, Department of Hospital Therapy No. 2

白俄罗斯, Bldg. 2, 8 Trubetskaya St., Moscow, 119992

Svetlana Rachina

Sechenov University

Email: Stchina@avetlana.Rantibiotic.ru
ORCID iD: 0000-0002-3329-7846

Dr.Sci. (Med.), Head of the Department of Hospital Therapy No. 2

白俄罗斯, Bldg. 2, 8 Trubetskaya St., Moscow, 119992

Vasily Mayorov

S.S. Yudin City Clinical Hospital

Email: Vasso88-88@bk.ru
ORCID iD: 0000-0001-5094-1261

Nephrologist

白俄罗斯, 4 Kolomensky proezd, Moscow, Russia, 115446

Dmitry Melnik

S.S. Yudin City Clinical Hospital

Email: melnik.nephro@gmail.com
ORCID iD: 0009-0006-3144-7165

Nephrologist

白俄罗斯, 4 Kolomensky proezd, Moscow, Russia, 115446

Svetlana Mirzakhamidova

S.S. Yudin City Clinical Hospital

Email: rimatevs@mail.ru
ORCID iD: 0000-0002-5807-5027

Cand.Sci. (Med.), Deputy Chief Physician for Medical Work

白俄罗斯, 4 Kolomensky proezd, Moscow, Russia, 115446

参考

  1. MacRae C., Mercer S.W., Guthrie B., et al. Comorbidity in chronic kidney disease: a large cross-sectional study of prevalence in Scottish primary care. Br. J. Gen. Pract. 2021;71(704):243–9. doi: 10.3399/bjgp20X714125.
  2. . Charles C., Ferris A.H. Chronic Kidney Disease. Prim. Care. 2020;47(4):585–95. doi: 10.1016/j.pop.2020.08.001.
  3. Ponticelli C., Doria A., Moroni G. Renal disorders in rheumatologic diseases: the spectrum is changing (Part 1: connective tissue diseases). J. Nephrol. 2021;34(4):1069–80. doi: 10.1007/s40620-020-00772-7.
  4. Kadowaki T., Maegawa H., Watada H., et al. Interconnection between cardiovascular, renal and metabolic disorders: A narrative review with a focus on Japan. Diab. Obes. Metab. 2022;24(12):2283–96. doi: 10.1111/dom.14829.

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2. Fig. Microscopic changes in kidney tissue. Hematoxylin and eosin staining, x400

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