Angiogenez

The research theme of angiogenesis - the development of blood vessels from the already existing is one of the
most financially supported medical scientific activities in the world. This is so, because 500 000 000 citizen need the therapeutic
correction of the pathologic angiogenesis processes. The review article is an assembly of the brightest research articles written
in and translated into Russian. The paper has several figures, prepared in an attempt to provide the understandable educational
resource. The biochemical and pathophysiological questions of angiogenesis are discussed in close relation to the modern
angiogenic pharmacotherapy. The objective of the article is to present the reader an opportunity to discover the biomedical
research challenge of the XXI century: the pathologic blood supply, vascularization and the associated phenomena.

angiogenesis, neovascularization, vascular endothelial growth factor, metastasis, cancer, malignant tumors, antiangiogenic pharmacotherapy