THE RESULTS OF USING SOME RAPID UREASE TESTS IN THE LABORATORY DIAGNOSIS OF HELICOBACTER PYLORI INFECTION
- Authors: LEONTYEVA N.I1, GRACHEVA N.M1, SHCHERBAKOV I.T1, KHRENNIKOV B.N2
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Affiliations:
- G.N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
- Infectious Diseases Hospital One, Moscow Healthcare Department
- Issue: No 4 (2012)
- Pages: 10-12
- Section: Articles
- URL: https://journals.eco-vector.com/2226-6976/article/view/275862
- ID: 275862
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Abstract
Objective. To estimate the rate of Helicobacter pylori infection in the gastric mucosa by rapid urease methods (HELIC test and HELPIL test) versus the results of histobacterioscopic examination. Subjects and methods. Two hundred and eighty-six patients with chronic gastrointestinal diseases associated with Helicobacter pylori were followed up. Their gastric biopsy specimens obtained at esophagogastroduodenoscopy and stained using the special procedure were examined. At the same time, the diagnosis of Helicobacter pylori infection was made applying the HELIC test and the HELPIL test. Results. The rate of Helicobacter pylori infection was 95.8±1.6%, as evidenced by a histobacterioscopic study. Comprehensive examination using the above rapid tests indicated that their results agreed with those of histobacterioscopy that is considered to be the gold standard in 89.3±2.4 and 92.4±2.4% of cases, respectively. Conclusion. The findings point to the high diagnostic value of these tests in diagnosing Helicobacter pylori infection.
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About the authors
N. I LEONTYEVA
G.N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
Email: leonteva-nina@yandex.ru
N. M GRACHEVA
G.N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
I. T SHCHERBAKOV
G.N. Gabrichevsky Moscow Research Institute of Epidemiology and Microbiology, Russian Inspectorate for the Protection of Consumer Rights and Human Welfare
B. N KHRENNIKOV
Infectious Diseases Hospital One, Moscow Healthcare Department
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