EXPERIENCE WITH A SET OF TEST SYSTEMS USED TO DIAGNOSE TORCH INFECTIONS

Objective. To generalize experience in practically using a set of enzyme immunoassay systems (ZAO «ECOlab») to diagnose TORCH infections. Materials and methods. The results of using the enzyme immunoassay systems «EIA-HSV-1+2-IgM», «EIA-HSV-1-IgG», «EIA-HSV-2-IgG», «EIA-CMV-IgM», «EIA-CMV-IgG», «EIA-Toxo-IgM», «EIA-Toxo-IgG», «EIA-Rubella-IgM», «EIA-Rubella-IgG», «EIA-CMV-IgG-avidity», and «EIA-HSV-1+2-IgG-avidity» to examine patients in the healthcare facilities of the Samara, Kaluga, and Lipetsk Regions were analyzed. Results. The real affection of the population in the above regions with TORCH infections was shown to be much higher than the official statistical data. The enzyme immunoassay tests assessing the avidity of IgG antibodies, which are in the above set, may be used without preliminary screening to examine cohorts of patients who are known a priori to have blood antibodies to the respective pathogens. Conclusion. The investigation has shown that there is a need for continuous laboratory monitoring of the respective risk groups: pregnancy-planning women and their sexual partners; pregnant women; neonates and infants less than 1 year old.

TORCH infections, laboratory diagnosis