MYCOPLASMA INFECTION AFTER VITAL ORGAN TRANSPLANTATION IN THE EARLY POSTOPERATIVE PERIOD


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Objective. To detect Mycoplasma species in solid organ transplant recipients following transplantation. Subjects and methods. Ninety-nine transplant recipients were examined for Mycoplasma infection after heart, liver, or kidney transplantation. The patients were divided into 2 groups: 1) 86 patients having a good postoperative period; 2) 13 patients whose postoperative period was poor. Mycoplasma antigens were determined by aggregate hemagglutination assay; antibodies were detected by the passive hemagglutination assay. Results. Markers of different Mycoplasma species were identified in patients after organ transplantation. In patients who had undergone orthotopic heart transplantation (OHT), Mycoplasma pneumoniae was identified almost twice more common than in those who had related liver fragments transplantation (RLFT): 54.5 ± 0.08 and 31.0 ± 0.09%, respectively (p < 0.05). Ureaplasma spp. also prevailed in patients who had undergone OHT versus those who had RLFT, but these data were not statistically significant (p > 0.05). Ureaplasma spp. was more frequently detected in Group 2 than in Group 1: its isolation frequency was 46.2 ± 0.14 and 36.0 ± 0.05%, respectively (p < 0.05). The isolation frequency of M. pneumoniae was 47.7 ± 0.05% in Group 1 and 30.8 ± 0.13% in Group 2 (p > 0.05). Conclusion. It is important to detect Mycoplasma not only for the prevention and treatment of its infection in the early in-hospital period, but also for the prevention of late complications.

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作者简介

L. GORINA

Email: lugor@bk.ru
Honored Academician N.F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of Russia Moscow, Russia

T. KRUPENIO

Email: ypsa89@mail.ru
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of Russia Moscow, Russia

E. GORSKAYA

Email: egorskaya@mail.ru
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of Russia Moscow, Russia

M. KORNILO

Email: livertranspl@mail.ru
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of Russia Moscow, Russia

I. TSIRULNIKOVA

Email: irish7@inbox.ru
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of Russia Moscow, Russia

S. GONCHAROVA

Email: info@gamaleya.org
Honored Academician N.F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of Russia Moscow, Russia

N. GAMOVA

Email: info@gamaleya.org
Honored Academician N.F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of Russia Moscow, Russia

I. RAKOVSKAYA

Email: rakovskaya35@mail.ru
Honored Academician N.F. Gamaleya Federal Research Center of Epidemiology and Microbiology, Ministry of Health of Russia Moscow, Russia

Nina GABRIELIAN

Email: labgso@mail.ru
V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, Ministry of Health of Russia Moscow, Russia

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