Seroepidemiological characteristics of hepatitis A in some areas of Central Federal District of Russia
- Authors: Asratyan A.A.1,2, Sipacheva N.B.1, Gotvyanskaya T.P.1, Ivanova M.Y.2, Semenenko T.A.1,2
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Affiliations:
- Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia
- I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
- Issue: No 4 (2018)
- Pages: 17-23
- Section: Articles
- URL: https://journals.eco-vector.com/2226-6976/article/view/287120
- DOI: https://doi.org/10.18565/epidem.2018.4.17-23
- ID: 287120
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Abstract
The problem of hepatitis A (HA) currently remains relevant, despite the changes in the epidemiological situation over the past decade and the improved prevention of this disease. Objective. To assess the epidemiological and serological characteristics of HA in some areas of the Russian Federation at the present stage. Materials and methods. The incidence of HA in the Federal Districts (FD) of the Russian Federation was analyzed. The epidemic situation in 6 (Moscow, Belgorod, Kaluga, Lipetsk, Tambov, and Tver) Regions of the Central FD was studied in detail; herd immunity was investigated in different population groups of these regions. The findings were statistically processed. Results. The incidence of FI A was found to have tended to decline among the population as a whole in the Russian Federation over the past 8 years. At the same time, the incidence rate in the North Caucasus, Ural and Siberian FDs exceeded the mean Russian rate by 2.5, 1.3 and 1.2 times, respectively. In the 6 regions of the Central FD, the mean annual HA rate was mainly higher than the mean district rate, but lower than that in the Russian Federation as a whole. The Kaluga Region is HA unfavorable, which is consistent with the high detection rate of anti-HA virus antibodies in this territory. The minimum HA morbidity rates were established in the Lipetsk Region, which corresponded to the results of a serological screening. Information on the recorded incidence of infectious disease does not always provide a clear picture of the true spread of infection. The serological studies showed that the Tver Region occupied the second place in the detection rate of anti-HA virus antibodies of the LgG class among the population (84.5%), while it ranked third by morbidity rates. Conclusion. The incidence of HA among the population as a whole of the Russian Federation, and in the Central FD tends to decrease, which causes a decline in herd immunity (mainly in the adult population) and in combination with a low level of community-level improvements in certain areas can lead to the higher incidence of HA.
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About the authors
Arpik A. Asratyan
Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Email: zasratyan@yahoo.com
MD, Leading Researcher; Professor, Department of Epidemiology
Natalia B. Sipacheva
Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia
Email: sipacheva@gamaleya.org
Cand. Med. Sсi., Senior Researcher
Tatiana P. Gotvyanskaya
Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia
Email: gotvian@gamaleya.org
Cand. Med. Sсi., Senior Researcher
Marina Yu. Ivanova
I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Email: ivanova_m_y@mail.ru
Cand. Med. Sсi., Associate Professor, Department of Histology, Cytology and Embryology
Tatiana A. Semenenko
Honored Academician N.F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of Russia
Email: semenenko@gamaleya.org
MD, Academician of the Russian Academy of Natural Sciences, Head, Department of Epidemiology; Professor, Department of Epidemiology
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