Immunological and clinical features of psoriasis in HIV-infected patients


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Abstract

Psoriasis is a systemic chronic, immunologically mediated, genetically determined disease that depends on environmental factors. It is detected in 2-3% of the world’s population. The review presents a current view on the etiology, pathogenesis, and clinical features of psoriasis in HIV-infected patients, on treatments and the possibility of their use in this category of patients. HIV infection is noted to affect the key components of the pathogenesis of psoriatic disease. Methods of psoriasis therapy and an approach to choosing its options are displayed. The authors’ personal archive photos of HIV-infected people suffering from psoriasis vulgaris have been used. In addition to HIV infection, these patients often have comorbidities that affect the course of psoriasis. The review has been carried out using the sources available in the search systems PubMed Services, Clinical Queries, and MEDIINEPlus. Unfortunately, the currently studied etiological and pathogenetic causes of the disease are not conclusively established. In this connection, the methods of psoriasis therapy will be further changed and improved, which indicates the importance of continuing investigations of this pathology in patients with HIV infection and the development of new treatments.

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About the authors

Evgeniy Y. Evdokimov

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: evdokimovevg@yandex.ru
Cand. Med. Sсi., Researcher

Aleksandr V. Sundukov

A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia

Email: sunducov1961@mail.ru
MD, Professor, Department of Infectious Diseases and Epidemiology

Elena A. Gorelova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: doctorgorelovaea@yandex.ru
Cand. Med. Sсi., Researcher, Clinical Department of Infectious Diseases

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