CHARACTERISTICS OF ENDOGENOUS INTOXICATION SYNDROME IN ACUTE ENTERIC INFECTIONS

The endogenous intoxication syndrome should be studied in patients with acute dysentery, food toxic infections, and salmonellosis, and food toxic infections to unravel the pathogenetic mechanisms underlying these diseases. For this, the authors estimated the level of low and medium molecular weight substances and their protein component (oligopeptides) in plasma, red blood cells, and urine over the course of these diseases. There was a relationship of the study values to the period and severity of the disease and to the completeness of recovery. The estimation of the level of low and medium molecular weight substances and oligopeptides in the plasma, red blood cells, and urine of patients with acute enteric infections may serve as a marker of the intoxication syndrome. The level of the study indicators may be used as additional criteria for the severity of the process, prediction of the development of the disease, and concurrence of complications, as well as a criterion for the completeness of recovery.

food toxic infections, dysentery, salmonellosis, low and medium molecular weight substances, oligopeptides, endogenous intoxication syndrome