Analysis of risk factors for non-adherence to follow-up and treatment for HIV infection: assessment of readiness to follow specialists’ recommendations


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Abstract

Objective. To analyze factors that can lead to non-adherence to follow-up and treatment, as well as the readiness ofpatients to visit specialists and to be treated for HIV infection. Subjects and methods. The investigation was conducted using the questionnaire method. Group 1 included 166 HIV-infected patients (91 men and 75 women) who were followed up in the Leningrad Regional Center for Prevention and Control of AIDS and Communicable Diseases. Group 2 consisted of 161 patients (84 men and 77 women) living with HIV who were followed up in the Republican Center for Prevention and Control of AIDS and Communicable Diseases, Ministry of Health of the Republic of Tatarstan. The median age in both groups was 39.0 [34; 45]years. Results. The risks of non-adherence were reported by 54.8% and 55.8% of the respondents in Groups 1 and 2, respectively. The risks associated with work were most significant in both groups (36.2 and 34.5% of the responses). The risks caused by the organizational features of providing care for HIV infection were more often called in Group 1 (p = 0.005); forgetfulness was in Group 2 (p = 0.006). An analysis of the self-assessment of readiness to regularly visit a physician and to take antiretroviral therapy (AR T) indicated that in Group 1, the median score was 9.5; 81.3% of the respondents stated their high readiness (more than 8 scores). In Group 2, the median score was 9.0; 91.9% of the respondents showed their high readiness. Conclusion. The risks usually associated directly with the convenience of taking ART and its tolerability seem to manifest themselves indirectly through the compliance of the follow-up and disease treatment regimens with lifestyle and labor activity. Each case of detecting the low indicators ofpatients’ readiness to visit a doctor and to take ART requires additional counseling, and the low readiness indicators themselves can be an indicator of risk in terms of maintaining adherence to follow-up and treatment for HIV infection.

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About the authors

Valentina V. Belyaeva

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: labora-et-ora@yandex.ru
МБ, Leading Researcher

Nadezhda V. Kozyrina

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: nad-kozyrina@yandex.ru
Cand. Med. Sci., Researcher

Ekaterina V. Sokolova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: ekaterinasokolova007@rambler.ru
Cand. Med. Sci., Researcher

Svetlana Y. Semikova

Leningrad Regional Center for Prevention and Control of AIDS and Communicable Diseases

Email: semsvet@list.ru
Deputy Chief

Niyaz I. Galiullin

Republican Center for Prevention and Control of AIDS and Communicable Diseases, Ministry of Health of the Republic of Tatarstan

Email: centre.spid@tatar.ru
Cand. Med. Sci, Head Physician

Elena P. Lebedeva

Leningrad Regional Center for Prevention and Control of AIDS and Communicable Diseases

Email: elenalebedeva@list.ru
Clinical Psychologist

Airat T. Beshimov

Republican Center for Prevention and Control of AIDS and Communicable Diseases, Ministry of Health of the Republic of Tatarstan

Email: beshimov@rambler.ru
Cand. Med. Sci., Deputy Chief Physician

Elena A. Khoraskina

Republican Center for Prevention and Control of AIDS and Communicable Diseases, Ministry of Health of the Republic of Tatarstan

Email: al_horaskina@mail.ru
Physician of the polyclinic

Artem N. Narkevich

Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University, Ministry of Health of Russia

Email: narkevichart@gmail.com
МD, Associate Professor, Head, Department of Medical Cybernetics and Informatics, Head, Laboratory of Medical Cybernetics and Management in Healthcare

Olga V. Gavrilova

Leningrad Regional Center for Prevention and Control of AIDS and Communicable Diseases

Email: olga7519@bk.ru
Social Work Specialist

Zoya K. Suvorova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: zksu@inbox.ru
Cand. Med. Sci., Senior Researcher

Olga N. Khokhlova

Central Research Institute of Epidemiology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: x.olia79@mail.ru
Cand. Med. Sci., Researcher

References

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  2. Van Beckhoven D., Florence E., de Wit S., Wyndham-Thomas C., Sasse A, van Oyen H. et al. Incidence rate, predictors and outcomes of interruption of HIV care: nationwide results from the Belgian HIV cohort. HIV Med. 2020; 21: 557-566. doi: 10.1111/hiv.12901
  3. Кольцова О.В. О развитии проактивности в лечебном процессе у пациентов с ВИЧ. Журнал инфектологии 2020; 12(3, приложение 1): 152.
  4. Беляева В.В., Козырина Н.В., Голиусова М.Д., Андреев А.В., Покровская А.В., Коннов В.В. Самооценка факторов риска нарушения приверженности лечению ВИЧ-инфекции: результаты опроса пациентов. В кн.: Покровский В.В., ред. Инфекционные болезни в современном мире: эпидемиология, диагностика, лечение и профилактика. Сборник трудов XII Ежегодного Всероссийского интернет-конгресса по инфекционным болезням с международным участием, 7-9 сентября 2020 г. М.: ММА, 2020; 31
  5. Беляева В.В. Базовые стратегии формирования приверженности при ВИЧ-инфекции: результаты опроса специалистов. Эпидемиол. инфекц. болезни. Актуал. вопр. 2019; 9(1): 43-47. doi: 10.18565/epidem. 2019.9.1.43-7

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