The Central Research Institute of Epidemiology has been in the service of diagnosis, therapy, and prevention of acute intestinal infections for 60 years

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Abstract

The overview article presents scientific and practical successes and achievements of the CRIE employees on the topical problems of acute intestinal infections (AIIs). It gives the main stages in the development of diagnosis, in the development of new algorithms for therapy and preventon of AIIs. The classification of dehydration in cholera has been first proposed and introduced into practice and a rationale is given for rehydration therapy for cholera-like diarrhea. Adequate current methods for deciphering the etiological pattern of infectious diarrheas have been developed; the clinical and epidemiological features of intestinal infections; the pathogenesis of diarrhea have been examined, and evidence-based current approaches to diagnosis, differential diagnosis and management tactics in a patient with AIIs.

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Viktor V. Maleev

Central Research Institute of Epidemology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Author for correspondence.
Email: maleyev@pcr.ru
ORCID iD: 0000-0001-5748-178X

RAS Full Member, Professor. Advisor of the Director for Research

Russian Federation, Moscow

Aleksandr V. Gorelov

Central Research Institute of Epidemology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: zdn@pcr.ru
ORCID iD: 0000-0001-9257-0171

MD, Academician of the Russian Academy of Sciences, Professor, Deputy Director for Scientific Work

Russian Federation, Moscow

Zhanna B. Ponezheva

Central Research Institute of Epidemology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: doktorim@mail.ru
ORCID iD: 0000-0002-6539-4878

MD, Leading Researcher, Clinical Department of Infectious Pathology

Russian Federation, Moscow

Zarema G. Tagirova

Central Research Institute of Epidemology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: tagirovaz05@mail.ru
ORCID iD: 0000-0001-6842-908X

MD, Leading Researcher, Clinical Department of Infectious Pathology

Russian Federation, Moscow

Denis V. Usenko

Central Research Institute of Epidemology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: dusenko@rambler.ru
ORCID iD: 0000-0001-5232-7337

MD, Leading Research Clinical Department of Infectious Pathology; Head, Educational Center

Russian Federation, Moscow

Elizaveta Yu. Grebenkina

Central Research Institute of Epidemology, Russian Federal Service for Supervision of Consumer Rights Protection and Human Well-Being

Email: Liza09@mail.ru
ORCID iD: 0000-0001-6567-1401

Laboratory Assistant-Researcher, Clinical Department of Infectious Pathology

Russian Federation, Moscow

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