Vol 4, No 2 (2016)

Articles

THE RAW MINERAL SALTS USE IN COSMETICS FORMULATIONS: ASSORTMENT, MINERAL RAW MATERIALS CHARACTERISTICS AND COSMETICS FORMULATION TECHNOLOGY

Evseeva S.B., Sysuev B.B.

Abstract

The application of mineral raw materials (brine lakes, thermal springs, sea water, bischofite) in cosmetics is presented in this article. The assortment of cosmetics that contain mineral salts is presented. The technological characteristics of production of these cosmetic formulations, in particular the ability of mineral salts to influence the stability of formulation and the sensory properties of products are given. The main approaches of that formulation development are described.
Pharmacy & Pharmacology. 2016;4(2):4-25
pages 4-25 views

POSSIBILITYIES OF PHYTOTHERAPY AT DIGESTIVE SYSTEM DISEASES

Kurkina A.V., Galyamova V.R., Kurkin V.A., Avdeeva E.V.

Abstract

In the present paper the modern approaches to the reasonable using of phytopharmaceuticals for diseases of gastrointestinal tract were discussed. Substantiates using groups of medicinal plants for the treatment of diseases of gastrointestinal tract based on important relationship «biologically active substance-pharmacological effect». According modern data of chemical composition and pharmacological activity in the attitude to this pathology the most important species of medicinal plants are considered. The importance of principle of phytotherapy’s safety as a main approach of evidential medicine was highlighted. This scientific paper will help experts to make an evidence-based decision of medicinal plants and phytopreparations based on them in clinical practice.
Pharmacy & Pharmacology. 2016;4(2):26-40
pages 26-40 views

BIOLOGICALLY ACTIVE SUBSTANCES OF PLANTS FROM SALIx L. GENUS

Frolova O.O., Kompantseva E.V., Dementieva T.M.

Abstract

The review systematizes data about chemical composition of bark, leaves, inflorescences, and sprouts of different species of Salix L. The closest attention is payed to investigations of Salix, which has been recently carried out in our country and abroad. For every group of biologically active substances described in Salix there are data about suppressed types of pharmacological activity.
Pharmacy & Pharmacology. 2016;4(2):41-59
pages 41-59 views

DETERMINATION OF ANTIMICROBIAL ACTIVITY OF ExTRACTS OF CALENDULA OFFICINALIS FLOWERS

Afanasyeva P.V., Kurkina A.V., Kurkin V.A., Lyamin A.V., Zhestkov A.V.

Abstract

Pot marigold (Calendula officinalis L.) is one of the most popular medicinal plants in the Russian Federation and abroad. The wide range of pharmacological activity of this medicinal plant is determined by carotenoids, flavonoids, saponins. These biologically active substances give total therapeutic effect of flowers of Calendula officinalis and medicines on base of pot marigold. This paper discusses the results of comparative investigations for a determination of antimicrobial activity of aqueous and aqueous-alcoholic extracts from pot marigold flowers. Detection of the minimum inhibitory concentration (MIC) was carried out by using the method of double serial dilutions in broth. The following microorganisms were used as test cultures: Bacillus cereus, Candida albicans, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus. The study showed that the widest spectrum of antibacterial activity has water extract of pot marigold flowers. As for Pseudomonas aeruginosa the most active medicine is tincture (1:10) with 70% alcohol. As for Escherichia coli the only phytopharmaceutical - water extract of marigold flowers, reveals antimicrobial activity. Against Bacillus cereus the most effective properties was indicated for tincture (1:5) with 70% ethanol and the liquid extract (1:2) with 70% alcohol. In case of Candida albicans, tincture (1:10) with 70% alcohol exhibited the highest activity.
Pharmacy & Pharmacology. 2016;4(2):60-70
pages 60-70 views

COMPARATIVE STUDY OF THE UV SPECTRA OF VARIOUS RAW MATERIALS OF URTICA DIOICA L

Balagozyan E.A., Kurkin V.A., Pravdivtseva O.E.

Abstract

Stinging nettle (Urtica dioica L.) is one of the famous and popular medicinal plants. In Russia the herbal materials are nettle’s leaves which have haemostatic effect. At the same time abroad the rhizomes and roots of nettle are the source of drugs with antitumor activity. The chemical composition of the rhizomes and roots of nettle is quite complicated and is represented by substances such as polysaccharides, lectins, sterols etc. The aim of the present study is the comparative phytochemical research of various parts of raw nettle by spectrophotometry. The study of extracts from various raw materials of nettle has shown, that the presence of flavonoids is peculiar for leaves, flowers and fruits. Sterols dominate in the rhizomes and roots of nettle. It was also noted that the UV-spectra of extracts of female inflorescences and fruits nettle have the same absorption maxima.
Pharmacy & Pharmacology. 2016;4(2):71-78
pages 71-78 views

MORPHOLOGICAL AND ANATOMICAL INVESTIGATIONS OF Chamenerion angustifolium (L.) SCOP.) GROWING IN THE NORTHERN CAUCASUS REGION

Serebryanaya F.K., Posevin I.I.

Abstract

The article covers the results of the study for micromorphological signs of leaf, stem, petiole of Chamenerion angustifolium (L.) Scop., from Onagraceae family, which grows in the Northern Caucasus, necessary to establish raw materials authenticity.
Pharmacy & Pharmacology. 2016;4(2):79-87
pages 79-87 views

ANALYSIS POLYVINYLPYRROLIDONE IN DOSAGE FORMS

Nikolaeva L.L., Gulyakin I.D., Oborotova N.A., Bunyatyan N.D.

Abstract

This article deals with the selection of the mobile and stationary phase for identifying polyvinylpyrrolidone formulations drug compounds by TLC.
Pharmacy & Pharmacology. 2016;4(2):88-94
pages 88-94 views

INVESTIGATION FOR THE INFLUENCE OF DIFFERENT MAGNESIUM SULFATE DOSES ON THE CONTENT OF CALCIUM AND CHLORIDE IN BLOOD SERUM OF RATS OF BOTH GENDERS

Voronkov A.V., Terekhov A.Y., Dyakova N.I., Avramenko N.S., Pozdnyakov D.I., Kuleshova S.A.

Abstract

We have conducted an investigation for the influence of different magnesium sulfate doses on the content of calcium and chloride in blood serum of rats of both genders. As the result of the study, we have established that peroral administration of magnesium sulfate at dose 1.7 g/kg leads to the significant decrease of chlorides content in blood serum of male rats, concerning the control group of animals, and at dose 5 g/kg to the decrease of concentration, chloride as well as calcium in rats of both genders.
Pharmacy & Pharmacology. 2016;4(2):95-100
pages 95-100 views

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