Assessment of the clinical course and outcomes of COVID-19 in vaccinated patients


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Abstract

COVID-19 is a global problem, the solution of which is possible only through vaccination. Purpose: to assess the predictive value of vaccination in relation to the course of a novel coronavirus infection and its outcomes. Material and methods. A comparative analysis of the clinical course and outcomes of COVID-19 was carried out among vaccinated (n=69) and unvaccinated patients (n=32) treated in the «Covid» hospital of the Republican Cardiology Dispensary of the Ministry of Healthcare of Chuvashia (RCD) from January to December 2021. Results. Vaccinated patients were less likely to be hospitalized in RCD, which indicates a more favorable course of COVID-19 in vaccinated patients. Unvaccinated patients were 2,5 times more likely to be admitted to the intensive care unit (ICU) and 3,8 times more likely to die at the hospital stage. Conclusion. Vaccination against COVID-19 does not exclude infection with a new coronavirus infection, but significantly reduces the risk of a severe course of a new coronavirus infection, admission to a hospital, intensive care unit, and, most importantly, significantly reduces the risk of death.

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About the authors

Nikolai A. Trofimov

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic; Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic; Federal Center for Traumatology, Orthopedics and Arthroplasty of the Ministry of Healthcare of Russia; Privolzhsky Research Medical University

Dr. med. habil., associate professor of the Department of surgical diseases and general surgery; professor of the Department of surgery, Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic, deputy chief physician for surgery

Larisa V. Tarasova

I.N. Ulyanov Chuvash State University; Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic; Surgut State University; Republican Clinical Hospital of the Ministry of Healthcare of the Chuvash Republic

Dr. med. habil., head of the Department of faculty and hospital therapy; professor of the Department of internal diseases, Medical Institute

Olga V. Dimitrieva

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic

assistant at the Department of faculty and hospital therapy; head of the Department of quality control and safety of medical activities

Vadim E. Babokin

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic; Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic

Email: babokin@bk.ru
Dr. med. habil., head of the Department of surgical diseases; professor of the Department of surgery

Alexandra V. Dubova

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic

PhD in Medicine, associate professor of the Department of faculty and hospital therapy; deputy chief medical officer

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