Assessment of the clinical course and outcomes of COVID-19 in vaccinated patients


Дәйексөз келтіру

Толық мәтін

Ашық рұқсат Ашық рұқсат
Рұқсат жабық Рұқсат берілді
Рұқсат жабық Рұқсат ақылы немесе тек жазылушылар үшін

Аннотация

COVID-19 is a global problem, the solution of which is possible only through vaccination. Purpose: to assess the predictive value of vaccination in relation to the course of a novel coronavirus infection and its outcomes. Material and methods. A comparative analysis of the clinical course and outcomes of COVID-19 was carried out among vaccinated (n=69) and unvaccinated patients (n=32) treated in the «Covid» hospital of the Republican Cardiology Dispensary of the Ministry of Healthcare of Chuvashia (RCD) from January to December 2021. Results. Vaccinated patients were less likely to be hospitalized in RCD, which indicates a more favorable course of COVID-19 in vaccinated patients. Unvaccinated patients were 2,5 times more likely to be admitted to the intensive care unit (ICU) and 3,8 times more likely to die at the hospital stage. Conclusion. Vaccination against COVID-19 does not exclude infection with a new coronavirus infection, but significantly reduces the risk of a severe course of a new coronavirus infection, admission to a hospital, intensive care unit, and, most importantly, significantly reduces the risk of death.

Толық мәтін

Рұқсат жабық

Авторлар туралы

Nikolai Trofimov

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic; Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic; Federal Center for Traumatology, Orthopedics and Arthroplasty of the Ministry of Healthcare of Russia; Privolzhsky Research Medical University

Dr. med. habil., associate professor of the Department of surgical diseases and general surgery; professor of the Department of surgery, Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic, deputy chief physician for surgery

Larisa Tarasova

I.N. Ulyanov Chuvash State University; Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic; Surgut State University; Republican Clinical Hospital of the Ministry of Healthcare of the Chuvash Republic

Dr. med. habil., head of the Department of faculty and hospital therapy; professor of the Department of internal diseases, Medical Institute

Olga Dimitrieva

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic

assistant at the Department of faculty and hospital therapy; head of the Department of quality control and safety of medical activities

Vadim Babokin

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic; Institute of Postgraduate Medical Education of the Ministry of Healthcare of the Chuvash Republic

Email: babokin@bk.ru
Dr. med. habil., head of the Department of surgical diseases; professor of the Department of surgery

Alexandra Dubova

I.N. Ulyanov Chuvash State University; Republican Cardiology Dispensary of the Ministry of Healthcare of the Chuvash Republic

PhD in Medicine, associate professor of the Department of faculty and hospital therapy; deputy chief medical officer

Әдебиет тізімі

  1. Rehman S.U., Rehman S.U., Yoo H.H. COVID-19 challenges and its therapeutics. Biomed Pharmacother. 2021; 142: 112015. https://dx.doi.org/10.1016/j.biopha.2021.112015.
  2. Трофимов Н.А., Бабокин В.Е., Егоров Д.В. с соавт. Опыт лечения миокардита у пациентов с COVID-19. Кардиология и сердечно-сосудистая хирургия. 2022; 15(2): 159-166. [Trofimov N.A., Babokin V.E., Egorov D.V. et al. Treatment of myocarditis in COVID-19 patients. Kardiologiya i serdechno-sosudistaya khirurgiya = Cardiology and Cardiovascular Surgery. 2022; 15(2): 159-166 (In Russ.)]. https://dx.doi.org/10.17116/kardio202215021159. EDN: GHJYMC.
  3. Никольский А.В., Волков Д.В., Федоровцев В.А. с соавт. Лечение острых артериальных тромбозов у пациентов с тяжелым течением новой коронавирусной инфекции. Кардиология и сердечно-сосудистая хирургия. 2022; 15(1): 13-18. [Nikolsky A.V., Volkov D.V., Fedorovtsev V.A. et al. Treatment of acute arterial thrombosis in patients with severe course of new coronavirus infection. Kardiologiya i serdechno-sosudistaya khirurgiya = Cardiology and Cardiovascular Surgery. 2022; 15(1): 13-18 (In Russ.)]. https://dx.doi.org/10.17116/kardio20221501113. EDN: BHULNS.
  4. Lopez Bernal J., Andrews N., Gower C. et al. Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: Test negative case-control study. BMJ. 2021; 373: n1088. https://dx.doi.org/10.1136/bmj.n1088.
  5. Alsaffar W.A., Alwesaibi A.A., Alhaddad M.J. et al. The effectiveness of COVID-19 vaccines in improving the outcomes of hospitalized COVID-19 patients. Cureus. 2022; 14(1): e21485. https://dx.doi.org/10.7759/cureus.21485.
  6. Verma A., Kumar I., Singh P.K. et al. Initial comparative analysis of pulmonary involvement on HRCT between vaccinated and nonvaccinated subjects of COVID-19. Eur Radiol. 2022; 32(6): 4275-83. https://dx.doi.org/10.1007/s00330-021-08475-8.
  7. Balachandran S., Moni M., Sathyapalan D.T. et al. A comparison of clinical outcomes between vaccinated and vaccine-naive patients of COVID-19, in four tertiary care hospitals of Kerala, South India. Clin Epidemiol Glob Health. 2022; 13: 100971. https://dx.doi.org/10.1016/j.cegh.2022.100971.
  8. Колобухина Л.В., Бургасова О.А., Кружкова И.С. с соавт. Оценка клинического течения COVID-19 у пациентов, вакцинированных «Спутник V», изменчивости RBD-домена S-белка SARS-CoV-2 и вируснейтрализующих свойств сыворотки. Вестник Российского государственного медицинского университета. 2021; 5: 66-75. [Kolobukhina L.V., Burgasova O.A., Kruzhkova I.S. et al. Assessment of COVID-19 clinical course in patients vaccinated with Spitnik V., SARS-CoV-2 S-protein RBD-domain variation and serum virus neutralizing activity. Vestnik Rossiyskogo gosudarstvennogo meditsinskogo universiteta = Herald of the Russian State Medical University. 2021; 5: 66-75 (In Russ.)]. https://dx.doi.org/10.24075/vrgmu.2021.046.
  9. Линец Ю.П., Артюхов С.В., Казанцев А.Н. с соавт. Течение COVID-19 у вакцинированных пациентов. Неотложная медицинская помощь. Журнал им. Н.В. Склифосовского. 2021; 10(4): 636-641. [Linets Yu.P., Artyukhov S.V., Kazantsev A.N. et al. COVID-19 course in vaccinated patients. Russian Sklifosovsky Journal of Emergency Medical Care. 2021; 10(4): 636-641 (In Russ.)]. https://dx.doi.org/10.23934/2223-9022-2021-10-4-636-641. EDN: HVZKXY.

Қосымша файлдар

Қосымша файлдар
Әрекет
1. JATS XML

© Bionika Media, 2022

Осы сайт cookie-файлдарды пайдаланады

Біздің сайтты пайдалануды жалғастыра отырып, сіз сайттың дұрыс жұмыс істеуін қамтамасыз ететін cookie файлдарын өңдеуге келісім бересіз.< / br>< / br>cookie файлдары туралы< / a>