EXPERIENCE WITH THE USE OF MELDONIUM IN LONG IMMOBILIZED PATIENTS WITH CEREBROVASCULAR DISEASES
- Authors: Shevtsova V.A.1, Vertkin A.L.1
-
Affiliations:
- A.I. Evdokimov Moscow State University of Medicine and Dentistry
- Issue: No 1 (2015)
- Pages: 8-12
- Section: Articles
- URL: https://journals.eco-vector.com/2412-4036/article/view/277217
- ID: 277217
Cite item
Abstract
One of the problems in the work of general practitioners and primary care physicians is the issue of rational management of bedridden elderly patients with comorbid pathology. The main cause of prolonged immobilization of elderly patients are cerebrovascular diseases (CVD). Management of these patients should include a comprehensive therapy, influencing on the few causes of the pathogenesis of underlying disease. The research of influence of meldonium in the complex therapy on blood pressure (BP) and lipid profile as the main risk factors for CVD was conducted. It is shown that the use of meldonium in the complex therapy of long-immobilized patients with CVD enhances the hypotensive and hypolipidemic effects, accelerates the achievement of the target values of blood pressure, as well as contributes to more efficient and rapid reduction in total cholesterol levels mainly due to triglycerides and low-density lipoprotein.
Full Text
![Restricted Access](https://journals.eco-vector.com/lib/pkp/templates/images/icons/text_lock.png)
About the authors
Viktoryia Aleksandrovna Shevtsova
A.I. Evdokimov Moscow State University of Medicine and Dentistry
Email: viktoriya.sams@mail.ru
postgraduate student, Department of Therapy, Clinical Pharmacology and Emergency Medical Care 127473 Moscow, 20/1, Delegatskaya st
Arkady Lvovich Vertkin
A.I. Evdokimov Moscow State University of Medicine and Dentistry
Email: kafedrakf@mail.ru
MD, Professor; Head of Department of Therapy, Clinical Pharmacology and Emergency Medical Care 127473 Moscow, 20/1, Delegatskaya st
References
- Щукин Ю.В., Рябов А.Е. Хроническая ишемическая болезнь сердца в пожилом и старческом возрасте. Пособие для врачей. Самара: Волга-Бизнес, 2008. 44 с.
- Косарев В.В. Бабанов С.А., Астахова А.В. Фармакология и лекарственная терапия. Под ред. В.К. Лепахина. М.: Эксмо, 2009. 480 с.
- Dambrova M., Daija D., Liepin'sh E., Kir'ianova O., Kalvin'sh I. Biochemical mechanisms of mildronate action during ischemic stress. Lik. Sprava. 2004;2:68-74.
- Dambrova M., Liepinsh E., Kalvinsh I. Mildronate: cardioprotective action through carnitine-lowering. Trends Cardiovasc Med. 2002; 12:275-9.
- Rafalski V.A., Brunet A. Energy metabolism in adult neural stem cell fate. Prog. Neurobiol. 2011 ;93:182-203.
Supplementary files
![](/img/style/loading.gif)