MODES OF ANTIMICROBIAL THERAPY AND PREVENTION OF EXACERBATIONS OF CHRONIC BRONCHITIS / CHRONIC OBSTRUCTIVE PULMONARY DISEASE
- Authors: Zaitsev A.A.1, Kryukov Y.V.1
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Affiliations:
- N.N. Burdenko Main Military Clinical Hospital
- Issue: No 1 (2016)
- Pages: 21-29
- Section: Articles
- URL: https://journals.eco-vector.com/2412-4036/article/view/277316
- ID: 277316
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Abstract
Article is devoted to antibiotic treatment of exacerbations of chronic bronchitis (CB) and chronic obstructive pulmonary disease (COPD), according to current clinical guidelines. It is noted that between the severity of the disease and the type of pathogen there is a described correlation. Modes of antimicrobial therapy, taking into account the likely exacerbation of pathogens depending on the severity of COPD are presented. In addition to the eradication of the pathogen, an important role in the prescription of antibiotic plays the possibility of increasing the length of time of remission. Among the major groups of antibiotics clinical efficacy was noted equally for each of them. Nevertheless the use of "respiratory" fluoroquinolones and amoxicillin/clavulanate, was characterized by a higher microbiological efficacy and lower incidence of recurrence of the disease compared with macrolides. Special attention is paid to vaccine preventable exacerbations of CB/COPD.
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About the authors
Andrey Alekseevich Zaitsev
N.N. Burdenko Main Military Clinical Hospital
Email: a-zaicev@yandex.ru
Yevgeny Vladimirovich Kryukov
N.N. Burdenko Main Military Clinical Hospital
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