PREVENTION AND TREATMENT OF COGNITIVE DISORDERS IN PATIENTS WITH HYPERTENSIVE ENCEPHALOPATHY


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Abstract

The literature review devoted to the evaluation of the etiopathogenetic mechanisms of the development of hypertensive encephalopathy (HE), and morphological features of brain damage in arterial hypertension (AH). The article highlights the role of uncontrolled or ineffectively controlled arterial hypertension as the most significant risk factor for the development of not only acute cerebrovascular accidents but also HE - a slowly progressive diffuse-focal brain lesions caused by chronic circulatory disturbance. Stages and clinical syndromes of HE are presented. The definition, classification and pathogenetic mechanisms of cognitive disorders are described. The importance of the use of psychological tests (Mini-Cog, etc.) for determining the severity of cognitive impairment is substantiated. The basic principles of HE treatment are considered. It is emphasized that at all stages of the HE, antihypertensive agents with organoprotective effects and neuroprotective drugs (ethylmethylhydroxypyridine succinate, citicoline, choline alphoscerate) should be prescribed.

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About the authors

Anna G. YEVDOKIMOVA

Email: aevdokimova@rambler.ru
MD, professor of the Department of hospital therapy №2, A.I. Yevdokimov Moscow state university of medicine and dentistry. 127473, Moscow, 20/1 Delegatskaya St

Yelena S. KIPARISOVA

MD, Advanced Training Institute of FMBA of Russia, Department of nervous diseases and neurostomatology. 125371, Moscow, 91 Volokolamskoe shosse

Yelena V. KOVALENKO

PhD, associate professor of the Department of hospital therapy №2, A.I. Yevdokimov Moscow state university of medicine and dentistry. 127473, Moscow, 20/1 Delegatskaya St

Vladimir V. YEVDOKIMOV

PhD, associate professor of the Department of hospital therapy №2, A.I. Yevdokimov Moscow state university of medicine and dentistry. 127473, Moscow, 20/1 Delegatskaya St

Lyudmila I. MARKOVA

MD, professor, Department of hospital therapy №2, A.I. Yevdokimov Moscow state university of medicine and dentistry. 127473, Moscow, 20/1 Delegatskaya St

Konstantin I. TEBLOEV

MD, professor, head of the Department of hospital therapy №2, A.I. Yevdokimov Moscow state university of medicine and dentistry 127473, Moscow, 20/1 Delegatskaya St

Iraida V. LARINA

PhD, Department of hospital therapy №2, A.I. Yevdokimov Moscow state university of medicine and dentistry 127473, Moscow, 20/1 Delegatskaya St

Anatoliy Ivanovich MARTYNOV

academician of Russian academy of sciences, MD, professor, Department of hospital therapy № 1, A.I. Yevdokimov Moscow state university of medicine and dentistry. 127473, Moscow, 20/1 Delegatskaya St

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