Graves’ disease in clinical practice of a therapist


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Abstract

Graves' disease is one of the most common autoimmune thyroid pathologies and it is the cause of hyperthyroidism in 70-80% cases. This disease has a dramatic clinical presentation, with both specific manifestations as development of goiter, thyroid-associated ophthalmopathy, pretibial myxedema, acropathy, and also nonspecific symptoms. Developing of hyperthyroidism is a main syndrome in clinical presentation. Hyperthyroidism is dangerous due to its severe consequences, such as development of cardiac pathology, disorders of carbohydrate and lipid metabolism, reproductive system disorders, neurological symptoms, pathology of bone tissue, affection of the visual system. Taking into account vast occurrence of nonspecific manifestations of Graves' disease, therapists often are the first who face the disease on its early stage. Therapists' knowledge of main clinical symptoms of Graves' disease will help to make a diagnosis; early visit to endocrinologist and prescription of appropriate treatment can quickly improve patient's condition and prevent possible complications.

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About the authors

Tatiana Yu. Demidova

N.I. Pirogov Russian National Research Medical University

Email: t.y.demidova@gmail.com
MD, professor, head of the Department of endocrinology

Tatiana V. Bolshakova

N.I. Pirogov Russian National Research Medical University

Email: miracle-84@bk.ru
assistant the Department of endocrinology

Yekaterina V. Bondarenko

M.F. Vladimirsky Moscow Regional Scientific Research Clinical Institute

researcher, Department of morbid anatomy

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