Modelling of parameters lipid a spectrum depending on age and size of an index of weight of a body at patients with clinical forms of ischemic illness of heart


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Aim. Modelling, lipid a spectrum, ischemic illness of heart. Materials and methods. The study included 210 patients with CAD with stable angina; 215 patients with CAD, who previously had myocardial infarction (MI), and 215 patients with CAD and heart failure (HF). Results. As have shown our calculations, the age of patients has the expressed value. So, at various structure of age groups parameters total cholesterol, LDL and HDL have mathematical distinctions at various groups of diseases. To evaluate lipid spectrum dependence on age and the BMI, analysis was conducted, visualized by ternary diagrams, with approximate equations. These approximate equations had grouping variables of the age of patients for each disease group and variables as total cholesterol, LDL and HDL, taking into account gender and the variables in the form. According to our calculations, the age of patients is clearly expressed. Thus, in different structure of various age groups, BMI such indicators total cholesterol, LDL and HDL, have mathematical differences in different groups of diseases. Conclusion. It is proved that dyslipidemia is essentially a biochemical manifestation of lipid metabolism disorders, which may result in significant morphological and functional disorders in the body. Our analysis revealed significant changes in the lipid spectrum, indicating a high risk of further development of atherosclerosis and its complications in the patients observed. Thus, mathematical models allow to calculate the values of total cholesterol, HDL and LDL, depending of age groups and BMI value in patients with myocardial infarction, angina, heart failure, taking gender into account.

Full Text

Restricted Access

About the authors

Boris B. Fishman

Yaroslav-the-Wise Novgorod State University

Email: fishman@mxc.ru
MD, рrofessor of Additional Professional Education Department, Institute For Medical Education

Alla I. Khorochevskaya

Novgorod regional clinical hospital

head physician of the Novgorod regional clinical hospital, candidate of medical sciences, competitor of a doctor's degree NovGu

Vacheslav V. Zurabov

Novgorod State University

postgraduate student (correspondence courses)

Antonina V. Savolyuk

Novgorod State University; Central Clinical Hospital

postgraduate student (correspondence courses); Head of Hospital №3

Natalia O. Zhbanova

Novgorod State University; Central Clinical Hospital

postgraduate student (correspondence courses); doctor, Hospital №4

Svetlana Sh. Butrimova

Yaroslav-the-Wise Novgorod State University

the senior teacher of faculty of internal illnesses NovGu, assistant to the head physician by a medical part, Great Novgorod, competitor NovGu

Irina V. Prozorova

Yaroslav-the-Wise Novgorod State University

candidate of medical sciences, the senior teacher of faculty of internal illnesses, competitor of a doctor's degree

David A. Shamiladze

Novgorod State University

postgraduate student (correspondence courses)

Oksana Yu. Lole

Central city clinical hospital

Managing therapeutic branch; competitor NovGu

References

  1. Klimov A.N., Nikulcheva N.G. Exchange lipid and lipoproteid and his infringements. SPb., 1999. 505 p.
  2. Adiposity. Under ред. I.I.Dedova and G.A.Melnichenko. M.: Medical news agency, 2004. 449 p.
  3. WHO. Obesity and overweight. Fact sheet N 311. Updated January 2015. Available at: http://www.who.int/mediacentre/ factsheets/fs311 /en/. Checked by 10.08.2016.
  4. Yumuk V., Tsigos C., Fried M., Schindler K., Busetto L., Micic D., Toplak H.; Obesity Management Task Force of the European Association for the Study of Obesity. European Guidelines for Obesity Management in Adults. Obes. Facts 2015;8:402-24.

Supplementary files

Supplementary Files
Action
1. JATS XML
Download

Copyright (c) 2017 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies