The role of vitamin D concentrations in the regulation of immunity and providing antiinfective protection in adults


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Abstract

Vitamin D, in addition to the regulation of phosphorus-calcium metabolism, provides a multilateral support for immunity. Fundamental and clinical studies have shown that vitamin D deficiency increases the risk of allergic rhinitis and pathologies associated with chronic systemic inflammation (atopic dermatitis, rheumatoid arthritis, inflammatory bowel disease, sepsis). Chronic inflammation and immunity disorders against the background of hypovitaminosis D significantly reduce the body's resistance to tuberculosis, viral hepatitis, acute respiratory infections, chronic bronchitis, and increases the risk of chronic obstructive pulmonary disease in adults. Evidence-based medicine data highlight the importance of the use of vitamin D preparations to support the immune system and anti-infection protection.

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About the authors

Olga A. Gromova

FSBEI HE «Ivanovo State Medical Academy» of RMH; Federal research center of informatics and management of RAS

Email: gromova@gmail.com
MD, рrofessor at the Department of Pharmacology; Senior staff scientist

Ivan Yuryevich Torshin

Federal research center of informatics and management of RAS

PhD in Physical and Mathematical Sciences, senior staff scientist

Anatoly Ivanovich Martynov

FSBEI HE «Moscow State Medical Stomatological University n.a. A.I. Evdokimov»

аcademician of RAS, МD, рrofessor at the Department of Hospital Therapy № 1

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