Clinical case: diagnosis of gastric cancer in a young patient


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详细

Poorly cohesive gastric carcinoma (signet ring cell carcinoma according to WHO classification, diffuse type of gastric cancer according to Lauren 1965 classification) is a type of cancer, consisting of cells that produce mucin, which displaces the nucleus to the periphery, which makes the cells look like a ring. One of the main causes of development is a mutation of the gene encoding the protein molecule E-cadherin (CDH1), which is responsible for intercellular connections and differentiation of epithelial cells. This case-report demonstrates the patient with signet ring cell carcinoma of the stomach and a discussion of the features of this type of cancer and diagnosis.

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作者简介

Inna Druk

Omsk State Medical University of the Ministry of Healthcare of Russia

MD, head of the Department of internal medicine and family medicine of continuing professional education

Alexey Pavlov

Regional Clinical Hospital, Omsk

head of pathological Department

Viktor Kosenok

Omsk State Medical University of the Ministry of Healthcare of Russia

MD, head of the Department of oncology, radiation therapy of continuing professional education

Elena Fadeeva

Omsk State Medical University of the Ministry of Healthcare of Russia

4th year student of the Faculty of medicine

Alexey Pavlov

Omsk State Medical University of the Ministry of Healthcare of Russia

3rd year student of the Faculty of medicine

Alexander Lyalyukov

Sochi State University

lecturer

Olga Drokina

Omsk State Medical University of the Ministry of Healthcare of Russia

PhD, associate professor of the Department of propedeutics of internal medicine

参考

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