Combined hypolipidemic therapy for mixed atherogenic dyslipidemia: review


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Abstract

High plasma levels of low-density lipoprotein cholesterol (LDL-C) and triglycerides (TG) in combination with reduced high-density lipoprotein cholesterol (HDL-C) level is a common dyslipidemia. Statin therapy effectively reduces LDL-C, but is not always sufficient to optimize the overall lipid profile, exposing the patient to residual cardiovascular risk. The analysis of current literature on the efficacy and safety of statins and fibric acid derivatives combination for the correction of mixed dyslipidemia and prevention of cardiovascular risk.

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About the authors

Olga I. Boeva

''Central State Medical Academy of the Presidential Executive Office

Email: box0271@mail.ru
MD, PhD, DMSci., professor of the Department of therapy, cardiology and functional diagnostics with the course of nephrology Moscow

Valentin A. Kokorin

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: valentinkokorin@yahoo.com
MD, PhD, DMSci., professor of the department of hospital therapy named after academician P.E. Lukomsky Moscow

Alesya A. Khripunova

Stavropol State Medical University of the Ministry of Healthcare of Russia

Email: fktcz2007@yandex.ru
MD, PhD, associate professor of the Department of public health and health care, medical prevention and informatics Moscow

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