Modern opportunities for treatment of patient having chronic heart failure with low ejection fraction

Cover Page

Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

Worldwide, the prevalence of chronic heart failure (CHF) is increasing every year, representing a serious medical and social problem. Medicinal drugs can help manage the symptoms of CHF and improve the prognosis in patients, but often the use of drug therapy alone may not be enough. Modern approaches to the treatment of CHF with low ejection fraction (CHFnEF), in addition to drug therapy, also include the use of various electrophysiological methods: implantation of cardioresynchronizing devices, cardioverter defibrillators, interventional treatment of arrhythmias. Article presents an analysis of a clinical case of successful treatment of a comorbid patient with severe CHFrEF using optimal drug therapy, as well as such interventional cardiac surgical interventions as implantation of a cardioresynchronization device with defibrillator function and radiofrequency ablation of arrhythmogenic heart zones.

Full Text

Restricted Access

About the authors

Grigory E. Roitberg

JSC «Meditsina» (Clinic of Academician Roitberg); N.I. Pirogov Russian National Research University of the Ministry of Healthcare of Russia

Author for correspondence.
Email: contact@medicina.com
ORCID iD: 0000-0003-0514-9114

MD, professor, academician of RAS, head of the Department of therapy, general medical practice and nuclear medicine of the Faculty of additional professional education; head

Russian Federation, Moscow; Moscow

Andrey V. Ardashev

M.V. Lomonosov Moscow State University

Email: ardashev@yahoo.com
ORCID iD: 0000-0003-1908-9802

MD, professor, Medical Scientific and Educational Center

Russian Federation, Moscow

Evgeniy G. Zhelyakov

JSC «Meditsina» (Clinic of Academician Roitberg)

Email: zheleu@rambler.ru
ORCID iD: 0000-0003-1865-8102

PhD in Medical Sciences, associate professor of the Department of cardiovascular surgery of the Faculty of additional professional education

Russian Federation, Moscow

Natalya V. Kondratova

JSC «Meditsina» (Clinic of Academician Roitberg); N.I. Pirogov Russian National Research University of the Ministry of Healthcare of Russia

Email: kondratova@medicina.ru
ORCID iD: 0000-0003-2421-0558

MD, professor of RAS, professor of the Department of therapy, general medical practice and nuclear medicine of the Faculty of additional professional education; head of hospital

Russian Federation, Moscow; Moscow

Larisa K. Merzyavko

JSC «Meditsina» (Clinic of Academician Roitberg)

Email: larisa.konst@gmail.com

doctor of functional diagnostics

Russian Federation, Moscow

Natalya K. Ponkina

N.I. Pirogov Russian National Research University of the Ministry of Healthcare of Russia

Email: bauhaus33@yandex.ru

resident of the Department of therapy, general medical practice and nuclear medicine of the Faculty of additional professional education

Russian Federation, Moscow

Irina D. Slastnikova

N.I. Pirogov Russian National Research University of the Ministry of Healthcare of Russia

Email: slastid@mail.ru
ORCID iD: 0000-0002-4076-2849

PhD in Medical Sciences, associate professor of the Department of therapy, general medical practice and nuclear medicine of the Faculty of additional professional education

Russian Federation, Moscow

Denis V. Sokolov

JSC «Meditsina» (Clinic of Academician Roitberg)

Email: sokolovdv@medicina.ru
ORCID iD: 0000-0002-5120-4594

PhD in Medical Sciences, cardiologist

Russian Federation, Moscow

References

  1. Clinical practice guidelines for chronic heart failure. Rossiyskiy kardiologicheskiy zhurnal = Russian Journal of Cardiology. 2020; 25(11): 311–374 (In Russ.). https://dx.doi.org/10.15829/1560-4071-2020-4083. EDN: LJGGQV.
  2. Kokorin V.A., Boeva O.I. Treatment of patients with chronic heart failure and reduced left ventricular ejection fraction: Is there a light at the end of the tunnel? Terapiya = Therapy. 2021; 7(5): 103–111 (In Russ.). https://dx.doi.org/10.18565/therapy.2021.5.103-111. EDN: XZMWIT.
  3. ESC Guidelines on cardiac pacing and cardiac resynchronization therapy. Rossiyskiy kardiologicheskiy zhurnal = Russian Journal of Cardiology. 2022; 27(7): 289–370 (In Russ.). https://dx.doi.org/10.15829/1560-4071-2022-5159. EDN: UTOLNY.
  4. clinical guidelines for atrial fibrillation and atrial flutter. Rossiyskiy kardiologicheskiy zhurnal = Russian Journal of Cardiology. 2021; 26(7): 190–260 (In Russ.). https://dx.doi.org/10.15829/1560-4071-2021-4594. EDN: FUZAAD.
  5. Chamberlain A.M., Redfield M.M., Alonso A. et al. Atrial fibrillation and mortality in heart failure: A community study. Circ Heart Fail. 2011; 4(6): 740–46. https://dx.doi.org/10.1161/CIRCHEARTFAILURE.111.962688.
  6. McMurray J.J.V., Solomon S.D., Inzucchi S.E. et al. Dapagliflozin in patients with heart failure and reduced ejection fraction. N Engl J Med. 2019; 381(21): 1995–2008. https://dx.doi.org/10.1056/NEJMoa1911303.
  7. Maddox T.M., Januzzi J.L., Allen L.A. et al. 2021 update to the 2017 ACC expert consensus decision pathway for optimization of heart failure treatment: Answers to 10 pivotal issues about heart failure with reduced ejection fraction: A report of the American College of Cardiology Solution Set Oversight Committee. J Am Coll Cardiol. 2021; 77(6): 772–810. https://dx.doi.org/10.1016/j.jacc.2020.11.022.
  8. Bokeria L.A., Neminushchiy N.M., Postol A.S. Cardiac resynchronization therapy. Indications and novel approaches to the improvement of its efficiency. Kompleksnyye problemy serdechno-sosudistykh zabolevaniy = Complex Issues of Cardiovascular Diseases. 2018; 7(3): 102–116 (In Russ.). https://dx.doi.org/10.17802/2306-1278-2018-7-3-102-116. EDN: VBHZZK.
  9. Shlyakhto E.V., Arutyunov G.P., Belenkov Yu.N., Ardashev A.V. Sudden cardiac death. Moscow: Medpraktika-M. 2015; 704 pp. (In Russ.). ISBN: 978-5-98803-349-3.
  10. Proietti R., Sagone A. Electrical storm: Incidence, prognosis and therapy. Indian Pacing Electrophysiol J. 2011; 11(2): 34–42.
  11. Postol A.S., Vygovsky A.B., Neminuschy N.M. ICD therapy at the present stage: opportunities to reduce inadequate shocks. Meditsinskiy al’manakh = Medical Almanac. 2018; (1): 88–95 (In Russ.). EDN: YWNRKZ.
  12. Talibullin I.V., Lebedeva N.B. Implantable cardioverter-defibrillators in the prevention of sudden cardiac death: current recommendations for use and real clinical practice (literature review). Byulleten’ sibirskoy meditsiny = Bulletin of Siberian Medicine. 2022; 21(1): 183–196 (In Russ.). https://dx.doi.org/10.20538/1682-0363-2022-1-183-196. EDN: CSKUZE.
  13. Ardashev A.V. Clinical arrhythmology. Vol. 3. Moscow: Medpraktika-M. 2021; 429 pp (In Russ.). ISBN: 978-5-98803-449-0.
  14. Blanck Z., Akhtar M. Ventricular tachycardia due to sustained bundle branch reentry: Diagnostic and therapeutic considerations. Clin Cardiol. 1993; 16(8): 619–22. https://dx.doi.org/10.1002/clc.4960160812.

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig.1. Electrocardiogram of patient L. from 2018

Download (195KB)
3. Fig.2. Ventricular tachycardia No. 1 registered in patient L. during Holter monitoring of electrocardiography in 2020

Download (283KB)
4. Fig.3. 12-lead surface electrocardiogram against the background of three-chamber cardiac stimulation after restoration of sinus rhythm in patient L. QRS complex width 140 ms (initial QRS duration-150 ms)

Download (154KB)
5. Fig.4. 12 leads of a surface electrocardiogram against the background of clinical ventricular extrasystole (Fig. 4.1. panel A) and stimulation mapping of clinical ventricular tachycardia No. 1 (Fig. 4.2. panel B) in the area of the free wall of the myocardium, closer to the posterolateral regions, at the border of the basal and middle third left ventricle

Download (348KB)
6. Fig.5. Three-dimensional amplitude reconstruction of the left atrium (front view), performed for patient L. using a non-fluoroscopic mapping system during radiofrequency ablation of atrial fibrillation

Download (157KB)
7. Fig.6. 12 leads of a surface electrocardiogram during ventricular tachycardia No. 2 (horizontal electrical axis of the heart, QRS configuration according to the type of right bundle branch block, QRS duration - 196 ms, transition zone V6, tachycardia cycle length 490 ms)

Download (275KB)
8. Fig.7. Sustained ventricular tachycardia No. 3 due to the circulation of the excitation front along the legs of the bundle of His (bundle branch re-entery)

Download (736KB)

Copyright (c) 2023 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies