Modern viewpoint at prediabetes: Prevalence, diagnostic criteria, risk groups, screening

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Abstract

Prediabetes is an important problem of our time, as it is not only a metabolic condition associated with a high risk of type 2 diabetes mellitus developing, but also has a role of independent predictor of the development of cardiovascular diseases and other complications. Quite often diabetes it is proceeding asymptomatic, and therefore current review considers the risk factors associated with prediabetes, basing on which the primary care physician will be able to examine the relevant group of patients more specifically. Despite existing generally accepted criteria, diagnosing prediabetes remains to be a quite complicated task, since the world’s leading experts do not agree on the threshold values for this condition. Use of comprehensive screening and lower glycemic values may lead to earlier detection of prediabetes and slow its further progression.

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About the authors

Vera N. Larina

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Author for correspondence.
Email: larinav@mail.ru
ORCID iD: 0000-0001-7825-5597
SPIN-code: 3674-9620

MD, Professor, Head of the Department of Polyclinic Therapy of the Faculty of General Medicine

Russian Federation, Moscow

Anton O. Lankin

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: lankin99_99@mail.ru
ORCID iD: 0000-0001-7922-3896
SPIN-code: 8731-5610

Resident of the Department of Outpatient Therapy of the Faculty of General Medicine

Russian Federation, Moscow

Vladimir G. Larin

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: larinvladimir@mail.ru
ORCID iD: 0000-0002-3177-3407
SPIN-code: 9394-2871

PhD in Medical Sciences, Associate Professor, Associate Professor of the Department of Polyclinic Therapy of the Faculty of General Medicine

Russian Federation, Moscow

Milada G. Golovko

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia

Email: larinav@mail.ru
ORCID iD: 0000-0003-2196-6739
SPIN-code: 2329-0384

PhD in Medical Sciences, Associate Professor, Associate Professor of the Department of Polyclinic Therapy of the Faculty of General Medicine

Russian Federation, Moscow

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Supplementary files

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2. Fig 1. Leading risk factors associated with prediabetes

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3. Fig. 2. Risk factors for diabetes according to the American Diabetes Association (ADA)

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4. Fig 3. Stratified approach to diabetes mellitus screening [35]

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