Infectious endocarditis in a patient with a transplanted kidney on a conventional hemodialysis
- Authors: Kozlova A.A.1, Agafonova Y.S.1, Timofeev R.G.1, Mayorov V.V.2, Merkusheva E.P.2, Kokorin V.A.1
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Affiliations:
- N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia
- O.M. Filatov Municipal Clinical Hospital No. 15 of the Department of Healthcare of Moscow
- Issue: Vol 9, No 9 (2023)
- Pages: 144-149
- Section: CLINICAL CASES
- URL: https://journals.eco-vector.com/2412-4036/article/view/626169
- DOI: https://doi.org/10.18565/therapy.2023.9.144-149
- ID: 626169
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Abstract
Infectious endocarditis remains challenging to diagnose, especially for patients with no apparent clinical symptoms. The presented clinical case describes a rapid progression of sepsis and challenges in treating a patient with risk factors, including undergoing immunosuppressive therapy due to a transplanted kidney, renal failure and the need for conventional dialysis. The case report highlights the significance of frequent monitoring of patients with the described risk factors, and emphasises the critical role of adopting more aggressive treatment strategies during the initial phases of the disease.
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About the authors
Anna A. Kozlova
N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia
Author for correspondence.
Email: annakoz15@mail.ru
ORCID iD: 0009-0002-4321-1927
Assistant at the Department of Hospital Therapy named after P.E. Lukomsky of the Faculty of General Medicine
Russian Federation, MoscowYulia S. Agafonova
N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia
Email: yuliaagaf2000@mail.ru
ORCID iD: 0009-0007-4877-9569
6th year student of the Faculty of General Medicine
Russian Federation, MoscowRoman G. Timofeev
N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia
Email: Timofrg@yandex.ru
ORCID iD: 0009-0000-2468-2200
6th year student of the Faculty of General Medicine
Russian Federation, MoscowVasily V. Mayorov
O.M. Filatov Municipal Clinical Hospital No. 15 of the Department of Healthcare of Moscow
Email: Vasso88-88@bk.ru
Head of the Department of Nephrology
Russian Federation, MoscowElena P. Merkusheva
O.M. Filatov Municipal Clinical Hospital No. 15 of the Department of Healthcare of Moscow
Email: lucky666_92@mail.ru
Nephrologist at the Department of Nephrology
Russian Federation, MoscowValentin A. Kokorin
N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia
Email: valentinkokorin@yahoo.com
ORCID iD: 0000-0001-8614-6542
MD, Associate Professor, Professor the Department of Hospital Therapy named after P.E. Lukomsky of the Faculty of General Medicine
Russian Federation, MoscowReferences
- McCreery R.J., Florescu D.F., Kalil A.C. Sepsis in immunocompromised patients without human immunodeficiency virus. J Infect Dis. 2020; 222(Suppl 2): S156–65. https://dx.doi.org/10.1093/infdis/jiaa320.
- Демин А.А., Кобалава Ж.Д., Скопин И.И. с соавт. Инфекционный эндокардит и инфекция внутрисердечных устройств у взрослых. Клинические рекомендации 2021. Российский кардиологический журнал. 2022; 27(10): 113–192. [Demin A.A., Kobalava Zh.D., Skopin I.I. et al. Infectious endocarditis and infection of intracardiac devices in adults. Clinical guidelines 2021. Rossiyskiy kardiologicheskiy zhurnal = Russian Journal of Cardiology. 2022; 27(10): 113–192 (In Russ.)]. https://dx.doi.org/10.15829/1560-4071-2022-5233. EDN: DCXUXV.
- Тюрин В.П., Шевченко Ю.Л. Инфекционные эндокардиты: руководство. 2-е изд., перераб. и доп. М.: ГЭОТАР-Медиа. 2013; 368 с. [Tyurin V.P., Shevchenko Yu.L. Infective endocarditis: A guide. 2nd ed., revised and additional. Moscow: GEOTAR-Media. 2013; 368 pp. (In Russ.)]. ISBN: 978-5-9704-2554-1.
- Chaudry M.S., Carlson N., Gislason G.H. et al. Risk of infective endocarditis in patients with end stage renal disease. Clin J Am Soc Nephrol. 2017; 12(11): 1814–22. https://dx.doi.org/10.2215/CJN.02320317.
- Nucifora G., Badano L.P., Viale P. et al. Infective endocarditis in chronic haemodialysis patients: An increasing clinical challenge. Eur Heart J. 2007; 28(19): 2307–12. https://dx.doi.org/10.1093/eurheartj/ehm278.
- Hoen B., Paul-Dauphin A., Hestin D., Kessler M. EPIBACDIAL: A multicenter prospective study of risk factors for bacteremia in chronic hemodialysis patients. JASN. 1998; 9(5): 869–76. https://dx.doi.org/10.1681/ASN.V95869.
- Hoen B., Alla F., Selton-Suty C. et al.; Association pour l’Etude et la Prévention de l’Endocardite Infectieuse (AEPEI) Study Group. Changing profile of infective endocarditis: Results of a 1-year survey in France. JAMA. 2002; 288(1): 75–81. https://dx.doi.org/10.1001/jama.288.1.75.
- Pericas J.M., Llopis J., Jimenez-Exposito M.J. et al. Infective endocarditis in patients on chronic hemodialysis. J Am Coll Cardiol. 2021; 77(13): 1629–40. https://dx.doi.org/10.1016/j.jacc.2021.02.014.
- Raza S., Hussain S.T., Rajeswaran J. et al. Value of surgery for infective endocarditis in dialysis patients. J Thorac Cardiovasc Surg. 2017; 154(1): 61–70.e6. https://dx.doi.org/10.1016/j.jtcvs.2017.02.063.
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