Hypokalemia in a patient with heart failure and atrial fibrillation as a predictor of life-threatening arrhythmia

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Atrial fibrillation (AF) is the most common arrhythmia in patients with heart failure (HF). Growing evidence indicates an interaction between hypokalemia and AF. The presented clinical case demonstrates one of the life-threatening complications of hypokalemia in a patient with HF and AF – development of ventricular fibrillation, which was successfully terminated by electropulse therapy and did not recur in the presence of antiarrhythmic therapy and hypokalemia correction. Low potassium level could be eliminated by titrating mineralocorticoid receptor antagonists. In addition, to increase K+ level in tissues, it is advisable to take drugs containing high doses of potassium and magnesium aspartate. This clinical example emphasizes the critical importance of adequate drug therapy to prevent life-threatening complications such as ventricular fibrillation.

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作者简介

Zoya Tatarintseva

Professor S.V. Ochapovsky Research Institute – Regional Clinical Hospital No. 1 of the Ministry of Healthcare of Krasnodar territory; Kuban State Medical University of the Ministry of Healthcare of Russia

编辑信件的主要联系方式.
Email: z.tatarintseva@list.ru
ORCID iD: 0000-0002-3868-8061

MD, PhD (Medicine), head of the Cardiology Department; assistant at the Department of cardiac surgery and cardiology of the Faculty of advanced training and professional retraining of specialists

俄罗斯联邦, Krasnodar; Krasnodar

Yulia Katushkina

Professor S.V. Ochapovsky Research Institute – Regional Clinical Hospital No. 1 of the Ministry of Healthcare of Krasnodar territory; Kuban State Medical University of the Ministry of Healthcare of Russia

Email: ukadoc@gmail.com
ORCID iD: 0009-0009-7334-9928

MD, endocrinologist at the Department of endocrinology; assistant at the Department of therapy No. 1 of the Faculty of advanced training and professional retraining of specialists

俄罗斯联邦, Krasnodar; Krasnodar

Elena Kosmacheva

Professor S.V. Ochapovsky Research Institute – Regional Clinical Hospital No. 1 of the Ministry of Healthcare of Krasnodar territory; Kuban State Medical University of the Ministry of Healthcare of Russia

Email: kosmachova_h@mail.ru
ORCID iD: 0000-0001-5690-2482

deputy chief physician for medical affairs; MD, Dr. Sci. (Medicine), professor, head of the Department of therapy No. 1 of the Faculty of advanced training and professional retraining of specialists

俄罗斯联邦, Krasnodar; Krasnodar

Olga Babicheva

Professor S.V. Ochapovsky Research Institute – Regional Clinical Hospital No. 1 of the Ministry of Healthcare of Krasnodar territory; Kuban State Medical University of the Ministry of Healthcare of Russia

Email: babolga@mail.ru
ORCID iD: 0000-0003-3010-492X

MD, PhD (Medicine), cardiologist; associate professor of the Department of cardiac surgery and cardiology of the Faculty of advanced training and professional retraining of specialists

俄罗斯联邦, Krasnodar; Krasnodar

参考

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  15. Государственный реестр лекарственных средств Минздрава России. Инструкции по медицинскому применению лекарственных препаратов с МНН калия аспарагинат + магния аспарагинат. Доступ: https://grls.rosminzdrav.ru/GRLS.aspx?RegNumber=&MnnR=Калия+аспарагинат%2bМагния+аспарагинат&lf=&TradeNmR=&OwnerName=&MnfOrg=&MnfOrgCountry=&isfs=0®type=1%2c6&pageSize=10&token=429c9023-dd79-4811-aa14-13d2e7ed8379&order=Registered&orderType=desc&pageNum=1 (дата обращения – 20.08.2024). [State Register of Medicines of the Ministry of Healthcare of Russia. Instructions for medical use of the medicinal products with INN potassium aspartate + magnesium aspartate. Registration certificate: ЛП-№(000178)-(РГ-RU). URL: https://grls.rosminzdrav.ru/GRLS.aspx?RegNumber=&MnnR=Калия+аспарагинат%2bМагния+аспарагинат&lf=&TradeNmR=&OwnerName=&MnfOrg=&MnfOrgCountry=&isfs=0®type=1%2c6&pageSize=10&token=429c9023-dd79-4811-aa14-13d2e7ed8379&order=Registered&orderType=desc&pageNum=1 (date of access – 20.08.2024) (In Russ.)].

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2. Fig. 1. Electrocardiogram of the observed patient on admission to the hospital

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3. Fig. 2. Electrocardiogram of an observed patient with paroxysm of ventricular fibrillation

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