Familial idiopathic basal ganglia calcification (Fahr disease)

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Abstract

Fahr disease is a rare genetic pathology proceeding with brain calcification. Magnetic resonance imaging of the brain has the decisive importance in its diagnosis. Current article describes clinical cases of Fahr disease, in which the clinical picture was manifested by cognitive, motor disorders and convulsive syndrome. Idiopathic calcification of basal ganglia is a relatively rare disease, understanding of the pathogenesis and clinical picture of which has significantly expanded our knowledge of neurodegenerative pathologies.

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About the authors

Ekaterina S. Ostapchuk

Tyumen State Medical University of the Ministry of Healthcare of Russia; Regional Clinical Hospital No. 1

Author for correspondence.
Email: ostapchukes2008@mail.ru
ORCID iD: 0000-0003-1176-4113
SPIN-code: 6877-6140

MD, PhD (Medicine), associate professor of the Department of neurology with a course in neurosurgery of the Institute of clinical medicine, head of the Department of neurology

Russian Federation, Tyumen; Tyumen

Anastasia A. Meng

Tyumen State Medical University of the Ministry of Healthcare of Russia; Regional Clinical Hospital No. 1

Email: nastya1398@bk.ru
ORCID iD: 0009-0000-2539-0816

MD, neurologist at the Department of neurology

Russian Federation, Tyumen; Tyumen

Andrey A. Vorobyov

Tyumen State Medical University of the Ministry of Healthcare of Russia

Email: avmvv@mail.ru
ORCID iD: 0009-0001-8169-0589

MD, neurologist at the Department of neurology

Russian Federation, Tyumen

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2. Fig. 1. Computed tomography of the brain of patient S.

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3. Fig. 2. Computed tomography of the brain of patient K.

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