Rapid course of severe diabetic retinopathy
- Autores: Nadybina M.N.1, Ushanova F.O.1, Demidova T.Y.1
-
Afiliações:
- N.I. Pirogov Russian National Research Medical University (Pirogov University) of the Ministry of Healthcare of Russia
- Edição: Volume 11, Nº 3 (2025)
- Páginas: 116-122
- Seção: CLINICAL CASES
- URL: https://journals.eco-vector.com/2412-4036/article/view/687142
- DOI: https://doi.org/10.18565/therapy.2025.3.116-122
- ID: 687142
Citar
Texto integral
Acesso aberto
Acesso está concedido
Acesso é pago ou somente para assinantes
Resumo
Progress in the treatment of vascular complications of diabetes mellitus (DM) has not solved the problem of timely diagnosis of diabetic retinopathy (DR), which is detected in most cases at an advanced stage of DM. DR is a common microvascular complication of DM and the leading cause of preventable blindness in people of working age. The presented clinical case demonstrates a patient with complete loss of vision in the first 6 years from the onset of type 2 DM. Despite multiple attempts of anti-VEGF therapy, proliferative retinopathy in this case was complicated by corneal dystrophy, rubeosis of iridis, terminal glaucoma, and development of blindness in both eyes. Due to the risk of rapid progression of DR, annual examination by ophthalmologist is critical to preserve patients’ vision and improve their quality of life. The article considers potential risk factors for severe DR, and discusses methods for early diagnosis and prevention of this complication.
Palavras-chave
Texto integral
Sobre autores
Margarita Nadybina
N.I. Pirogov Russian National Research Medical University (Pirogov University) of the Ministry of Healthcare of Russia
Autor responsável pela correspondência
Email: mita0098@gmail.com
ORCID ID: 0000-0002-6891-1711
MD, postgraduate student of the Department of endocrinology of the Institute of Clinical Medicine
Rússia, 117513, Moscow, 1/6 Ostrovityanova St.Fatima Ushanova
N.I. Pirogov Russian National Research Medical University (Pirogov University) of the Ministry of Healthcare of Russia
Email: fati_2526@mail.ru
ORCID ID: 0000-0001-5512-6899
Código SPIN: 3361-8564
MD, PhD (Medicine), associate professor of the Department of endocrinology of the Institute of Clinical Medicine
Rússia, 117513, Moscow, 1/6 Ostrovityanova St.Tatyana Demidova
N.I. Pirogov Russian National Research Medical University (Pirogov University) of the Ministry of Healthcare of Russia
Email: t.y.demidova@gmail.com
ORCID ID: 0000-0001-6385-540X
Código SPIN: 9600-9796
MD, Dr. Sci. (Medicine), professor, head of the Department of endocrinology of the Institute of Clinical Medicine
Rússia, 117513, Moscow, 1/6 Ostrovityanova St.Bibliografia
- Amoaku WM, Ghanchi F, Bailey C, Banerjee S, Banerjee S, Downey L et al. Diabetic retinopathy and diabetic macular oedema pathways and management: UK Consensus Working Group. Eye (Lond). 2020;34(Suppl 1):1–51. PMID: 32504038. PMCID: PMC7337227. https://doi.org/10.1038/s41433-020-0961-6
- Клинические рекомендации. Сахарный диабет: ретинопатия диабетическая, макулярный отек диабетический. Общероссийская общественная организация «Ассоциация врачей-офтальмологов», Российская ассоциация эндокринологов. Рубрикатор клинических рекомендаций Минздрава России. 2023. ID: 115_2. Доступ: https://cr.minzdrav.gov.ru/preview-cr/115_2 (дата обращения – 25.04.2025). [Clinical guidelines. Diabetes mellitus: Diabetic retinopathy, diabetic macular edema. Association of Ophthalmologists, Russian Association of Endocrinologists. Rubricator of clinical guidelines of the Ministry of Healthcare of Russia. 2023. ID: 115_2. URL: https://cr.minzdrav.gov.ru/preview-cr/115_2 (date of access – 25.04.2025) (In Russ.)].
- Абдулаева Э.А., Минхузина Э.Л., Кусков А.Н. Анти-VEGF терапия пролиферативной диабетической ретинопатии: от исследований к реальной клинической практике. РМЖ. Клиническая офтальмология. 2020;20(2):97–103. [Abdulaeva EA, Minkhuzina EL, Kuskov AN. Anti-VEGF therapy for proliferative diabetic retinopathy: Translating research evidence into clinical practice. Russkiy meditsinskiy zhurnal. Klinicheskaya oftalmologiya = Russian Medical Journal. Clinical Ophthalmology. 2020;20(2):97–103 (In Russ.)]. EDN: UUAGIV. https://doi.org/10.32364/2311-7729-2020-20-2-97-103
- Головин A.C., Беликова Е.И., Кожухов А.А., Эскина Э.Н., Кумар В. Диабетическая ретинопатия: современные эпидемиологические, патогенетические, диагностические, хирургические аспекты (обзор). Саратовский научно-медицинский журнал. 2022;18(4):667–671. [Golovin AS, Belikova EI, Kozhukhov AA, Eskina EN, Kumar V. Diabetic retinopathy: Modern epidemiological, pathogenetic, diagnostic, surgical aspects (review). Saratovskiy nauchno-meditsinskiy zhurnal = Saratov Journal of Medical Scientific Research. 2022;18(4):667–671 (In Russ.)]. EDN: WJWBCV.
- Алгоритмы специализированной медицинской помощи больным сахарным диабетом (11-й выпуск). Под ред. И.И. Дедова, М.В. Шестаковой, А.Ю. Майорова. М.: ООО «Типография „Печатных дел мастер“» 2023; 231 с. [Algorithms of specialized medical care for patients with diabetes mellitus (issue 11). Edited by Dedov II, Shestakova MV, Mayorov AYu. M.: Printing House of Printmakers Master. 2023; 231 pp. (In Russ.)]. ISBN: 978-5-6048675-4-9. https://doi.org/10.14341/DM13042
- Wright WS, Eshaq RS, Lee M, Kaur G, Harris NR. Retinal physiology and circulation: Effect of diabetes. Compr Physiol. 2020;10(3):933–74.PMID: 32941691. PMCID: PMC10088460. https://doi.org/10.1002/cphy.c190021
- Tavakoli M, Petropoulos IN, Malik RA. Assessing corneal nerve structure and function in diabetic neuropathy. Clin Exp Optom. 2012;95(3):338–47.PMID: 22594548. https://doi.org/10.1111/j.1444-0938.2012.00743.x
- Childs C, Barker LA, Gage AM, Loosemore M. Investigating possible retinal biomarkers of head trauma in Olympic boxers using optical coherence tomography. Eye Brain. 2018;10:101–10.PMID: 30588143. PMCID: PMC6299469. https://doi.org/10.2147/eb.s183042
- Демидова Т.Ю., Кожевников А.А. Диабетическая ретинопатия: история, современные подходы к ведению, перспективные взгляды на профилактику и лечение. Сахарный диабет. 2020;23(1):95–105. [Demidova TYu, Kozhevnikov AA. Diabetic retinopathy: History, modern approaches to management, prospective views of prevention and treatment. Sakharnyy diabet = Diabetes Mellitus. 2020;23(1):95–105 (In Russ.)].EDN: ECFMZS. https://doi.org/10.14341/dm10273
- Галимова А.Б., Галимова В.У. Анти-VEGF-терапия в лечении гемофтальма на фоне пролиферативной диабетической ретинопатии. Офтальмологические ведомости. 2020;13(4):83–88. [Galimova AB, Galimova VU. Anti-VEGF therapy in treatment of vitreous hemorrhage due to proliferative diabetic retinopathy. Oftalmologicheskie vedomosti = Ophthalmology Reports. 2020;13(4):83–88 (In Russ.)].EDN: AQZUZS. https://doi.org/10.17816/OV42466
- Сомов Е.Е. Клиническая офтальмология: руководство для врачей. 3-е изд. М.: МЕДпресс-информ. 2012; 398 с. [Somov EE. Clinical ophthalmology: Guide for doctors. 3rd edition. Moscow: MEDpress-inform. 2012; 398 pp. (In Russ.)]. ISBN: 978-5-98322-703-3. EDN: QMBGZT.
Arquivos suplementares
