Systemic lupus erythematosus and lymphadenopathy in a young male patient

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Systemic lupus erythematosus is a systemic autoimmune disease of unknown etiology that develops in genetically predisposed patients under the influence of numerous external factors. A clinical case of systemic lupus erythematosus in 31-year-old male patient with the development of splenomegaly, lymphadenopathy, and lupus nephritis is described in the article. At the outpatient stage, the clinical picture was represented by periodic fever and articular syndrome in the form of polyarthralgia and volatile arthritis. Introduced case was particular because of the need to exclude lymphoproliferative disease in a patient with significant immunological indexes (ANF HEp2, ANA screen, ENA-screen, antibodies to dsDNA, C3, C4) due to severe lymphadenopathy. Diagnosis of lymphoproliferative disease was excluded after lymph node biopsy.

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作者简介

Natalia Bulanova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; G.R. Derzhavin Tambov State University

编辑信件的主要联系方式.
Email: bulanovanatalia@mtu-net.ru

MD, Dr. Sci. (Medicine), associate professor of the Department of therapy, general medical practice and nuclear medicine,  professor of the Department of hospital therapy

俄罗斯联邦, 117997, Moscow, 1 Ostrovityanova St.; Tambov

Lyudmila Panchenkova

Russian University of Medicine of the Ministry of Healthcare of Russia

Email: lapanchenkova@mail.ru

MD, Dr. Sci. (Medicine), professor of the Department of hospital therapy No. 1

俄罗斯联邦, 127473, Moscow, 20/1 Delegatskaya St.

Khadizhat Khamidova

Russian University of Medicine of the Ministry of Healthcare of Russia

Email: k.khamidova@mail.ru

MD, PhD (Medicine), associate professor of the Department of hospital therapy No. 1

俄罗斯联邦, 127473, Moscow, 20/1 Delegatskaya St.

Elena Ulyanova

Russian University of Medicine of the Ministry of Healthcare of Russia

Email: klepa13@list.ru

MD, PhD (Medicine), associate professor of the Department of hospital therapy No. 1

俄罗斯联邦, 127473, Moscow, 20/1 Delegatskaya St.

Svetlana Ivanova

N.A. Semashko Clinical Hospital “RZhD-Medicine”

Email: ivanova.revm@mail.ru

MD, PhD (Medicine), head of the rheumatology center

俄罗斯联邦, 109386, Moscow, 23/1 Stavropolskaya St.

Kristina Ryzhkova

N.A. Semashko Clinical Hospital “RZhD-Medicine”

Email: Sedunova@mail.ru

MD, rheumatologist

俄罗斯联邦, 109386, Moscow, 23/1 Stavropolskaya St.

Tatiana Khomyakova

N.A. Semashko Clinical Hospital “RZhD-Medicine”

Email: info@semashko.com

MD, chief physician

俄罗斯联邦, 109386, Moscow, 23/1 Stavropolskaya St.

Vladimir Popov

N.A. Semashko clinical hospital “RZhD- Medicine”; Medical Institute of Continuous Education of Moscow State University of Food Production

Email: clinpharmcb6@mail.ru

MD, Dr. Sci. (Medicine), clinical pharmacologist, professor of the Department of pharmacy

俄罗斯联邦, 109386, Moscow, 23/1 Stavropolskaya St.; Moscow

参考

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