Systemic lupus erythematosus and lymphadenopathy in a young male patient

Capa

Citar

Texto integral

Acesso aberto Acesso aberto
Acesso é fechado Acesso está concedido
Acesso é fechado Acesso é pago ou somente para assinantes

Resumo

Systemic lupus erythematosus is a systemic autoimmune disease of unknown etiology that develops in genetically predisposed patients under the influence of numerous external factors. A clinical case of systemic lupus erythematosus in 31-year-old male patient with the development of splenomegaly, lymphadenopathy, and lupus nephritis is described in the article. At the outpatient stage, the clinical picture was represented by periodic fever and articular syndrome in the form of polyarthralgia and volatile arthritis. Introduced case was particular because of the need to exclude lymphoproliferative disease in a patient with significant immunological indexes (ANF HEp2, ANA screen, ENA-screen, antibodies to dsDNA, C3, C4) due to severe lymphadenopathy. Diagnosis of lymphoproliferative disease was excluded after lymph node biopsy.

Texto integral

Acesso é fechado

Sobre autores

Natalia Bulanova

N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; G.R. Derzhavin Tambov State University

Autor responsável pela correspondência
Email: bulanovanatalia@mtu-net.ru

MD, Dr. Sci. (Medicine), associate professor of the Department of therapy, general medical practice and nuclear medicine,  professor of the Department of hospital therapy

Rússia, 117997, Moscow, 1 Ostrovityanova St.; Tambov

Lyudmila Panchenkova

Russian University of Medicine of the Ministry of Healthcare of Russia

Email: lapanchenkova@mail.ru

MD, Dr. Sci. (Medicine), professor of the Department of hospital therapy No. 1

Rússia, 127473, Moscow, 20/1 Delegatskaya St.

Khadizhat Khamidova

Russian University of Medicine of the Ministry of Healthcare of Russia

Email: k.khamidova@mail.ru

MD, PhD (Medicine), associate professor of the Department of hospital therapy No. 1

Rússia, 127473, Moscow, 20/1 Delegatskaya St.

Elena Ulyanova

Russian University of Medicine of the Ministry of Healthcare of Russia

Email: klepa13@list.ru

MD, PhD (Medicine), associate professor of the Department of hospital therapy No. 1

Rússia, 127473, Moscow, 20/1 Delegatskaya St.

Svetlana Ivanova

N.A. Semashko Clinical Hospital “RZhD-Medicine”

Email: ivanova.revm@mail.ru

MD, PhD (Medicine), head of the rheumatology center

Rússia, 109386, Moscow, 23/1 Stavropolskaya St.

Kristina Ryzhkova

N.A. Semashko Clinical Hospital “RZhD-Medicine”

Email: Sedunova@mail.ru

MD, rheumatologist

Rússia, 109386, Moscow, 23/1 Stavropolskaya St.

Tatiana Khomyakova

N.A. Semashko Clinical Hospital “RZhD-Medicine”

Email: info@semashko.com

MD, chief physician

Rússia, 109386, Moscow, 23/1 Stavropolskaya St.

Vladimir Popov

N.A. Semashko clinical hospital “RZhD- Medicine”; Medical Institute of Continuous Education of Moscow State University of Food Production

Email: clinpharmcb6@mail.ru

MD, Dr. Sci. (Medicine), clinical pharmacologist, professor of the Department of pharmacy

Rússia, 109386, Moscow, 23/1 Stavropolskaya St.; Moscow

Bibliografia

  1. Aringer M., Costenbader K., Daikh D. et al. 2019 European League Against Rheumatism / American College of Rheumatology classification criteria for systemic lupus erythematosus. Arthritis Rheumatol. 2019; 71(9): 1400–12. https://doi.org/10.1002/art.40930. PMID: 31385462. PMCID: PMC6827566.
  2. Асеева Е.А., Дубиков А.И., Левашева Л.А. с соавт. Регистр пациентов с системной красной волчанкой, Евразийская когорта (РЕНЕССАНС). Научно-практическая ревматология. 2016; 54(5): 520–526. [Aseeva E.A., Dubikov A.I., Levasheva L.A. et al. The registry of systemic lupus erythematosus patients, a Eurasian cohort (RENAISSANCE). Sovremennaya revmatologiya = Modern Rheumatology Journal. 2016; 54(5): 520–526 (In Russ.)]. EDN: YUAXTN.
  3. Федеральные клинические рекомендации по диагностике и лечению системной красной волчанки. Ассоциация ревматологов России. 2013. Доступ: https://rheumatolog.ru/files/clinrec/sistemnaya_krasnaya_volchanka_.doc (дата обращения – 12.11.2024). [Federal clinical guidelines for the diagnosis and treatment of systemic lupus erythematosus. Association of Rheumatologists of Russia. 2013. URL: https://rheumatolog.ru/files/clinrec/sistemnaya_krasnaya_volchanka_.doc (date of access – 12.11.2024) (In Russ.)].
  4. Клюквина Н.Г., Ведерникова Е.А., Ломанова Г.В. Особенности системной красной волчанки у мужчин: описание случаев и данные литературы. Современная ревматология. 2013; 7(4): 26–32. [Klyukvina N.G., Vedernikova E.A., Lomanova G.V. Specific features of systemic lupus erythematosus in males: Case reports and literature data. Sovremennaya revmatologiya = Modern Rheumatology Journal. 2013; 7(4): 26–32 (In Russ.)]. https://doi.org/10.14412/1996-7012-2013-2435. EDN: RPYINR.
  5. Клинические рекомендации. Диагностика и лечение волчаночного нефрита. Ассоциация нефрологов, Научное общество нефрологов России, общероссийская общественная организация нефрологов «Российское диализное общество». 2021. Доступ: https://rusnephrology.org/wp-content/uploads/2021/09/lupus.pdf (дата обращения – 12.11.2024). [Clinical guidelines. Diagnosis and treatment of lupus nephritis. Association of Nephrologists, Scientific Society of Nephrologists of Russia, Russian Dialysis Society. 2021. URL: https://rusnephrology.org/wp-content/uploads/2021/09/lupus.pdf (date of access – 12.11.2024) (In Russ.)].
  6. Calguneri M., Ozturk M.A., Ozbalkan Z. et al. Frequency of lymphadenopathy in rheumatoid arthritis and systemic lupus erythematosus. J Int Med Res. 2003; 31(4): 345–49. https://doi.org/10.1177/147323000303100415. PMID: 12964513.
  7. Melikoglu M.A., Melikoglu M. The clinical importance of lymphadenopathy in systemic lupus erythematosus. Acta Reumatol Port. 2008; 33(4): 402–6. PMID: 19107085.
  8. Zhou Z., Liu H., Yang Y. et al. The five major autoimmune diseases increase the risk of cancer: Epidemiological data from a large-scale cohort study in China. Cancer Commun (Lond). 2022; 42(5): 435–46. https://doi.org/10.1002/cac2.12283. PMID: 35357093. PMCID: PMC9118055.

Arquivos suplementares

Arquivos suplementares
Ação
1. JATS XML

Declaração de direitos autorais © Bionika Media, 2024