Systemic lupus erythematosus and lymphadenopathy in a young male patient
- Authors: Bulanova N.A.1,2, Panchenkova L.A.3, Khamidova K.A.3, Ulyanova E.A.3, Ivanova S.M.4, Ryzhkova K.A.4, Khomyakova T.D.4, Popov V.V.5,6
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Affiliations:
- N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia
- G.R. Derzhavin Tambov State University
- Russian University of Medicine of the Ministry of Healthcare of Russia
- N.A. Semashko Clinical Hospital “RZhD-Medicine”
- N.A. Semashko clinical hospital “RZhD- Medicine”
- Medical Institute of Continuous Education of Moscow State University of Food Production
- Issue: Vol 10, No 9 (2024)
- Pages: 147-151
- Section: CLINICAL CASES
- URL: https://journals.eco-vector.com/2412-4036/article/view/646573
- DOI: https://doi.org/10.18565/therapy.2024.9.147-151
- ID: 646573
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Abstract
Systemic lupus erythematosus is a systemic autoimmune disease of unknown etiology that develops in genetically predisposed patients under the influence of numerous external factors. A clinical case of systemic lupus erythematosus in 31-year-old male patient with the development of splenomegaly, lymphadenopathy, and lupus nephritis is described in the article. At the outpatient stage, the clinical picture was represented by periodic fever and articular syndrome in the form of polyarthralgia and volatile arthritis. Introduced case was particular because of the need to exclude lymphoproliferative disease in a patient with significant immunological indexes (ANF HEp2, ANA screen, ENA-screen, antibodies to dsDNA, C3, C4) due to severe lymphadenopathy. Diagnosis of lymphoproliferative disease was excluded after lymph node biopsy.
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About the authors
Natalia A. Bulanova
N.I. Pirogov Russian National Research Medical University of the Ministry of Healthcare of Russia; G.R. Derzhavin Tambov State University
Author for correspondence.
Email: bulanovanatalia@mtu-net.ru
MD, Dr. Sci. (Medicine), associate professor of the Department of therapy, general medical practice and nuclear medicine, professor of the Department of hospital therapy
Russian Federation, 117997, Moscow, 1 Ostrovityanova St.; TambovLyudmila A. Panchenkova
Russian University of Medicine of the Ministry of Healthcare of Russia
Email: lapanchenkova@mail.ru
MD, Dr. Sci. (Medicine), professor of the Department of hospital therapy No. 1
Russian Federation, 127473, Moscow, 20/1 Delegatskaya St.Khadizhat A. Khamidova
Russian University of Medicine of the Ministry of Healthcare of Russia
Email: k.khamidova@mail.ru
MD, PhD (Medicine), associate professor of the Department of hospital therapy No. 1
Russian Federation, 127473, Moscow, 20/1 Delegatskaya St.Elena A. Ulyanova
Russian University of Medicine of the Ministry of Healthcare of Russia
Email: klepa13@list.ru
MD, PhD (Medicine), associate professor of the Department of hospital therapy No. 1
Russian Federation, 127473, Moscow, 20/1 Delegatskaya St.Svetlana M. Ivanova
N.A. Semashko Clinical Hospital “RZhD-Medicine”
Email: ivanova.revm@mail.ru
MD, PhD (Medicine), head of the rheumatology center
Russian Federation, 109386, Moscow, 23/1 Stavropolskaya St.Kristina A. Ryzhkova
N.A. Semashko Clinical Hospital “RZhD-Medicine”
Email: Sedunova@mail.ru
MD, rheumatologist
Russian Federation, 109386, Moscow, 23/1 Stavropolskaya St.Tatiana D. Khomyakova
N.A. Semashko Clinical Hospital “RZhD-Medicine”
Email: info@semashko.com
MD, chief physician
Russian Federation, 109386, Moscow, 23/1 Stavropolskaya St.Vladimir V. Popov
N.A. Semashko clinical hospital “RZhD- Medicine”; Medical Institute of Continuous Education of Moscow State University of Food Production
Email: clinpharmcb6@mail.ru
MD, Dr. Sci. (Medicine), clinical pharmacologist, professor of the Department of pharmacy
Russian Federation, 109386, Moscow, 23/1 Stavropolskaya St.; MoscowReferences
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