Clinical guidelines and real antimicrobial pharmacotherapy of patients with rhinosinusitis

The pharmacotherapy of inflammatory diseases of the parana-sal sinuses of 104 patients was analyzed, which were hospitalized to the otorhinolaryngological department in the period from January 2020 to December 2021. All patients were divided into two groups: group 1 (n=28) - with acute polysinusitis, group 2 (n=76) - with chronic polysinusitis. According to the results of a bacteriological study, 38,2% investigations of the total number were positive in the first group, 75% - in the second group. The main causative agents of sinusitis were S. aureus and S. epidermidis. In both groups, most of the patients received ceftriaxone 2 g/day, which does not take into account the current guidelines for curbing the growth of antibiotic resistance.

acute sinusitis, chronic sinusitis, antimicrobials, antibiotic resistance