Clinical guidelines and real antimicrobial pharmacotherapy of patients with rhinosinusitis
- Authors: Batishcheva G.A1, Vlasenkova A.A1, Goncharova N.Y.1, Cherenkova O.V1
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Affiliations:
- Voronezh State Medical University named after N.N. Burdenko
- Issue: No 4S (2022): Supplement
- Pages: 14-18
- Section: Articles
- URL: https://journals.eco-vector.com/2412-4036/article/view/276970
- DOI: https://doi.org/10.18565/therapy.2022.4suppl.14-18
- ID: 276970
Cite item
Abstract
The pharmacotherapy of inflammatory diseases of the parana-sal sinuses of 104 patients was analyzed, which were hospitalized to the otorhinolaryngological department in the period from January 2020 to December 2021. All patients were divided into two groups: group 1 (n=28) - with acute polysinusitis, group 2 (n=76) - with chronic polysinusitis. According to the results of a bacteriological study, 38,2% investigations of the total number were positive in the first group, 75% - in the second group. The main causative agents of sinusitis were S. aureus and S. epidermidis. In both groups, most of the patients received ceftriaxone 2 g/day, which does not take into account the current guidelines for curbing the growth of antibiotic resistance.
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About the authors
G. A Batishcheva
Voronezh State Medical University named after N.N. Burdenko
A. A Vlasenkova
Voronezh State Medical University named after N.N. Burdenko
N. Yu Goncharova
Voronezh State Medical University named after N.N. Burdenko
O. V Cherenkova
Voronezh State Medical University named after N.N. Burdenko
References
- Давидович Н.В., Кукалевская Н.Н., Башилова Е.Н., Бажукова Т.А. Основные принципы эволюции антибиотикорезистентности у бактерий (обзор литературы). Клиническая лабораторная диагностика. 2020; 6: 387-393. doi: 10.18821/0869-2084-2020-65-6-387-393.
- Федорова О.С., Федосенко С.В., Федотова М.М., Чигрина В.П. Антибактериальная терапия и отношение к проблеме антибиотикорезистентности во врачебной практике. Профилактическая медицина. 2021; 10: 106-118. doi: 10.17116/profmed202124101106.
- Акимкин В.Г., Тутельян А.В., Шулакова Н.И., Воронин Е.М. Пандемия COVID-19: новый виток нарастания антибиотикорезистентности. Инфекционные болезни. 2021; 3: 133-138. doi: 10.20953/1729-9225-2021-3-133-138.
- Орлова Ю.Ю., Сперанская Е.М., Никифорова П.Л., Мясникова И.А. Воспалительные заболевания околоносовых пазух в Чувашской республике. Антибактериальная терапия в оториноларингологии. 2019; 96-100.
- Клинические рекомендации. Острый синусит. Национальная медицинская ассоциация оториноларингологов. 2021. Рубрикатор клинических рекомендаций Минздрава России. ID: 313. Доступ: https://cr.minzdrav.gov.ru/schema/313_2 (дата обращения - 04.04.2022).
- Gregory J., Huynh B., Tayler B. et al. High-dose vs standard-dose amoxicillin plus clavulanate for adults with acute sinusitis: A randomized clinical trial. JAMA Netw Open. 2021; 4(3): e212713. doi: 10.1001/jamanetworkopen.2021.2713.