Clinical guidelines and real antimicrobial pharmacotherapy of patients with rhinosinusitis


Cite item

Full Text

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription or Fee Access

Abstract

The pharmacotherapy of inflammatory diseases of the parana-sal sinuses of 104 patients was analyzed, which were hospitalized to the otorhinolaryngological department in the period from January 2020 to December 2021. All patients were divided into two groups: group 1 (n=28) - with acute polysinusitis, group 2 (n=76) - with chronic polysinusitis. According to the results of a bacteriological study, 38,2% investigations of the total number were positive in the first group, 75% - in the second group. The main causative agents of sinusitis were S. aureus and S. epidermidis. In both groups, most of the patients received ceftriaxone 2 g/day, which does not take into account the current guidelines for curbing the growth of antibiotic resistance.

Full Text

Restricted Access

About the authors

G. A Batishcheva

Voronezh State Medical University named after N.N. Burdenko

A. A Vlasenkova

Voronezh State Medical University named after N.N. Burdenko

N. Yu Goncharova

Voronezh State Medical University named after N.N. Burdenko

O. V Cherenkova

Voronezh State Medical University named after N.N. Burdenko

References

  1. Давидович Н.В., Кукалевская Н.Н., Башилова Е.Н., Бажукова Т.А. Основные принципы эволюции антибиотикорезистентности у бактерий (обзор литературы). Клиническая лабораторная диагностика. 2020; 6: 387-393. doi: 10.18821/0869-2084-2020-65-6-387-393.
  2. Федорова О.С., Федосенко С.В., Федотова М.М., Чигрина В.П. Антибактериальная терапия и отношение к проблеме антибиотикорезистентности во врачебной практике. Профилактическая медицина. 2021; 10: 106-118. doi: 10.17116/profmed202124101106.
  3. Акимкин В.Г., Тутельян А.В., Шулакова Н.И., Воронин Е.М. Пандемия COVID-19: новый виток нарастания антибиотикорезистентности. Инфекционные болезни. 2021; 3: 133-138. doi: 10.20953/1729-9225-2021-3-133-138.
  4. Орлова Ю.Ю., Сперанская Е.М., Никифорова П.Л., Мясникова И.А. Воспалительные заболевания околоносовых пазух в Чувашской республике. Антибактериальная терапия в оториноларингологии. 2019; 96-100.
  5. Клинические рекомендации. Острый синусит. Национальная медицинская ассоциация оториноларингологов. 2021. Рубрикатор клинических рекомендаций Минздрава России. ID: 313. Доступ: https://cr.minzdrav.gov.ru/schema/313_2 (дата обращения - 04.04.2022).
  6. Gregory J., Huynh B., Tayler B. et al. High-dose vs standard-dose amoxicillin plus clavulanate for adults with acute sinusitis: A randomized clinical trial. JAMA Netw Open. 2021; 4(3): e212713. doi: 10.1001/jamanetworkopen.2021.2713.

Supplementary files

Supplementary Files
Action
1. JATS XML

Copyright (c) 2022 Bionika Media

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies