OPPORTUNITIES OF IMPROVEMENT OF CONTROL OF BLOOD PRESSURE IN PATIENTS WITH ARTERIAL HYPERTENSION AND ORTHOSTATIC ABNORMALITIES DUE TO TYPE 1 DIABETES
- 作者: Shchekotov V.V1, Shanko Z.G2
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隶属关系:
- E.A. Wagner Perm State Academy of Medicine
- Clinical health care hospital № 1
- 期: 编号 3 (2015)
- 页面: 35-38
- 栏目: Articles
- URL: https://journals.eco-vector.com/2412-4036/article/view/277267
- ID: 277267
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详细
In patients with diabetes mellitus (DM) type 1 in combination with arterial hypertension (AH), autonomic vegetative neuropathy is often manifested by orthostatic hypotension. The purpose of this study was to analyze the effectiveness of antihypertensive therapy of ACE inhibitors and antidiabetic therapy in combination with protector of veins in patients with hypertension, diabetes mellitus type 1 and orthostatic disorders (OD). 200 hypertensive patients with type 1 diabetes were examined, in 60 of which OD were revealed. Patients with hypertension, diabetes and OD were divided into two subgroups: patients from the first subgroup have received basic antihypertensive and intensify insulin therapy and additionally protector of veins in a dose of 1000 mg/day divided into 2 doses; patients from the second subgroup have been receiving only basic therapy consisting of ACE inhibitor and intensified insulin therapy. Achieving of target BP with ACE inhibitor monotherapy in patients with hypertension and type 1 diabetes was complicated by worsening existing OD. The combination of antihypertensive therapy with diosmine restores the physiological response in the active orthostatic test in patients with hypertension and type 1 diabetes, leading to the achievement of optimal blood pressure in 90% of patients.
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作者简介
V. Shchekotov
E.A. Wagner Perm State Academy of Medicine
Email: healthpro@mail.ru
MD, Professor; Head of Department of Internal Medicine and Outpatient Therapy 614990, Permskyi krai, Perm, 26, Petropavlovskaya st
Zh. Shanko
Clinical health care hospital № 1
Email: healthpro@mail.ru
Doctor of Emergency Department 614077, Permskyi krai, Perm, 68, Gagarina Boulevard
参考
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