SAS Enterprise Guide 6.1 for physicians: multiple comparisons

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Abstract

Objective: to develop algorithm of multiple comparisons data of prospective non-randomized clinical trial AMIRI – CABG (ClinicalTrials.gov Identifier: NCT03050489) using SAS Enterprise Guide 6.1.

Materials and methods. Data collection was performed according prospective non-randomized clinical trial AMIRI — CABG in Pavlov First St. Petersburg State Medical University, Saint Petersburg, Russia between 2016–2019 years with 336 patients. There is database with clinical, laboratory and instrumental data. Multiple comparisons test was performed with SAS Enterprise Guide 6.1.

Results. There was developed algorithm of multiple comparisons data of prospective non-randomized clinical trial AMIRI — CABG for independent group. This algorithm could be useful for physicians and researchers for data analysis.

Conclusion. Presented algorithm of data analysis could make easier and improve efficient data analysis. SAS Enterprise Guide 6.1 allows fast and accurate process data

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About the authors

Nikolay S. Bunenkov

Pavlov First Saint Petersburg State Medical University

Author for correspondence.
Email: bunenkov2006@gmail.com
ORCID iD: 0000-0003-4331-028X

aspirant, Department of Faculty Surgery

Russian Federation, Saint Petersburg

Gulnara F. Bunenkova

Pavlov First Saint Petersburg State Medical University

Email: gulnara533@gmail.com

resident, Department of Hospital Therapy

Russian Federation, Saint Petersburg

Vladimir V. Komok

Pavlov First Saint Petersburg State Medical University

Email: vladimir_komok@mail.ru
ORCID iD: 0000-0002-3834-7566
SPIN-code: 3572-5180

PhD, cardiac surgeon, Department of Cardiac Surgery No. 2

Russian Federation, Saint Petersburg

Oleg A. Grinenko

Pavlov First Saint Petersburg State Medical University

Email: klinika@spb-gmu.ru

Doctor of Medical Science, Vice-Rector

Russian Federation, Saint Petersburg

Alexander S. Nemkov

Pavlov First Saint Petersburg State Medical University

Email: nemk_as@mail.ru
ORCID iD: 0000-0002-5152-0001
SPIN-code: 2853-4634

Doctor of Medical Science, Professor, cardiac surgeon, Chief of Department of Cardiac Surgery No. 2

Russian Federation, Saint Petersburg

References

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  3. Унгуряну Т.Н., Гржибовский А.М. Сравнение трех и более независимых групп с использованием непараметрического критерия Краскела – Уоллиса в программе Stata // Экология человека. – 2014. – № 6. – C. 55–58. [Unguryanu TN, Grjibovski AM. Analysis of three independent groups using non-parametric Kruskal-Wallis test in Stata software. Ecology, human. 2014;(6):55-58. (In Russ.)]

Supplementary files

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2. Fig. 1. Multiple comparisons test with Bonferroni adjustment for independent group

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3. Fig. 2. Multiple comparisons test with Bonferroni adjustment results, boxplots. Age, years, median — horizontal line, mean — rhombus, outliers — dots, CPBType-groups: 1 — off-pump, 2 — on-pump, 3 — pump-assisted

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4. Fig. 3. Multiple comparisons test with Bonferroni adjustment results: no difference between three independent groups

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5. Fig. 4. Multiple comparisons test with Bonferroni adjustment results. Difference between three groups, troponin logarithm (ng/ml), median — horizontal line, mean — rhombus, outliers — dots, CPBType-groups: 1 — off-pump, 2 — on-pump, 3 — pump-assisted

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6. Fig. 5. Kruskal-Wallis test with multiple pairwise comparisons with adjustment

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Copyright (c) 2020 Bunenkov N.S., Bunenkova G.F., Komok V.V., Grinenko O.A., Nemkov A.S.

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