Determination of the trace element composition of human hair

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Abstract

Hair is one of the promising non-invasive samples for monitoring the trace element composition of the human body. But it is necessary to take into account the individual and subpopulation characteristics of sample donors. In this work, we experimentally studied the features of the analysis of human hair samples for the determination of trace elements by arc atomic emission spectrometry using a dry residue after acid mineralization. Validation was carried out by comparative analysis by the method used, as well as by atomic emission spectrometry with inductively coupled plasma. It has been shown that the concentrations of Al, B, Ca, Cu, Fe, Mg, Mn, P, Pb, Zn in a set of 50 samples from different donors obey the lognormal law, and therefore, the geometric mean (or median) is preferable as mean value. The content of Ca and Mg is higher in the female hair, while the content of Pb is higher in the male hair. The concentrations of Fe, Mn, and Pb are slightly higher in the hair of smokers than in non-smokers, but this difference is not statistically significant (probably due to the small sample size). Although the concentrations of several elements (including Mg, Mn, and P) differ in the hair of donors living in different regions of Russia, we failed to establish a significant difference of this factor. Positive correlations were found between the contents of some elements, in particular, Mg/Ca, Al/Fe, Al/P, Cu/Fe, Cu/P, Fe/P, weaker relationships were found for Al/Cu, Ca/Mn, Cu/Pb, Mn/P.

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About the authors

S. S. Savinov

Saint Petersburg State University

Author for correspondence.
Email: sergey.savinov.spb@gmail.com
ORCID iD: 0000-0002-7214-5917

Ph.D. (Chem.), senior lecturer of the Department of Analytical Chemistry

Russian Federation, Saint Petersburg, Russia

N. A. Riadchikova

Saint Petersburg State University

Email: elle-nat@mail.ru
ORCID iD: 0000-0001-7608-9011
Russian Federation, Saint Petersburg, Russia

T. M. Pikalova

Saint Petersburg State University

Email: tiana.pikalova@gmail.com
ORCID iD: 0000-0002-1106-9789
Russian Federation, Saint Petersburg, Russia

A. I. Drobyshev

Saint Petersburg State University

Email: s.sergei.s@mail.ru
ORCID iD: 0000-0002-9174-2055

Dr.Sci. (Phys.-math.), Professor

Russian Federation, Saint Petersburg, Russia

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