Analysis of methods for modeling deep defects of the skin and articular cartilage on laboratory animals in the experiment
- Authors: Izbulatov D.D.1, Varlamova N.V.1, Mikhailov V.E.1, Markin I.V.1, Erdniev A.L.1, Potapov P.K.1, Utkin Y.A.2
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Affiliations:
- Military Innovative Technopolis “ERA”
- Ural Research Institute of Composite Materials
- Issue: Vol 23, No 3 (2023)
- Pages: 77-88
- Section: Analytical reviews
- Published: 29.03.2024
- URL: https://journals.eco-vector.com/MAJ/article/view/516569
- DOI: https://doi.org/10.17816/MAJ516569
- ID: 516569
Cite item
Abstract
The creation and implementation of new methods and means of local treatment of wounds occurs in stages, however, a number of difficulties arise at each stage. The article discusses one of the main problems that arise at the preclinical stage when modeling deep defects of the skin and articular cartilage – the difficulty of accurately reproducing full-layer defects of the skin and articular tissue. Various factors influencing the success of such modeling also investigated, including the type of animal, the size of the defect and its location.
Keywords
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About the authors
Daulet D. Izbulatov
Military Innovative Technopolis “ERA”
Email: izbulatov98@mail.ru
senior operator of 3rd scientific company
Russian Federation, AnapaNatalia V. Varlamova
Military Innovative Technopolis “ERA”
Email: varlamova@tpu.ru
ORCID iD: 0000-0002-6100-2427
SPIN-code: 9139-6019
Cand. Sci. (Technol.), Senior Research Associate
Russian Federation, AnapaVladimir E. Mikhailov
Military Innovative Technopolis “ERA”
Email: mikhaylov.ve@yandex.ru
senior operator of 3rd scientific company
Russian Federation, AnapaIlya V. Markin
Military Innovative Technopolis “ERA”
Email: ilya.markin.92@bk.ru
ORCID iD: 0000-0002-9334-910X
SPIN-code: 6021-7645
Cand. Sci. (Technol.), Senior Research Associate
Russian Federation, AnapaArtur L. Erdniev
Military Innovative Technopolis “ERA”
Email: arti-erd@mail.ru
senior operator of 3rd scientific company
Russian Federation, AnapaPetr K. Potapov
Military Innovative Technopolis “ERA”
Email: forwardspb@mail.ru
SPIN-code: 5979-4490
MD, Cand. Sci. (Med.), Deputy Head of Department of Biomedical Research
Russian Federation, AnapaYurii A. Utkin
Ural Research Institute of Composite Materials
Author for correspondence.
Email: uautkin@yandex.ru
Deputy General Director for Medical Direction
Russian Federation, PermReferences
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