Genetics of multifactor diseases. Diagnoctic and predictive significance of endogenous risk factors

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Abstract

In review the new genetic approaches for the decision of problems of profound diagnostics, prognosis and optimization of therapy common diseases are considered. Is shown, that only modern molecular technologies allow solving scale tasks of revealing of association between the genetic status of individuals and their predisposition to certain most important and often diseases. The present period can be characterized as the period of accumulation of the information for decisive break in the field of quantitative molecular genetics of common disease. Most perspective for the decision of the put tasks is microchip technology, which allows simultaneously to identify multiple single nucleotide markers and to estimate levels expression of set of genes.

About the authors

V. I. Mazurov

St. Petersburg Academy of Postgraduate Education; Research Institute of Experimental Medicine of the RAMS

Author for correspondence.
Email: shabanov@mail.rcom.ru

Член-корреспондент РАМН

Russian Federation, St. Petersburg; St. Petersburg

M. M. Shavlovsky

St. Petersburg Academy of Postgraduate Education; Research Institute of Experimental Medicine of the RAMS

Email: shabanov@mail.rcom.ru
Russian Federation, St. Petersburg; St. Petersburg

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