Quality of life in carotid stenosis

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Abstract

There is a lack of evidence concerning the influence of occlusive carotid disease upon the health-related quality of life (HR-QOL). The aim of the study has been to reveal this influence and to determine whether carotid endarterectomy (CEA) and nonoperative treatment improve the HR-QOL of patients with carotid stenosis.

97 patients with symptomatic carotid stenosis were examined using the Quality of Life Enjoyment and Satisfaction Questionnaire. The degree of stenosis was more than 60% in all cases.

We have revealed impairment of the main determinants of the HR-QOL in 89,7 % patients. Factors, which most negatively influence the HR-QOL are presence of contralateral occlusive carotid disease, history of ischemic stroke, arterial hypertension and diabetes mellitus. The patients’ age, gender, the degree and side of the atherosclerotic lesion were not found to decrease the main parameters of the quality of life. Psychiatric symptoms, such as depression, and severe cognitive impairment also contribute to patients’ HR-QOL worsening. Patients, who underwent carotid endarterectomy, show a greater improvement of the HR-QOL than those treaed non operatively. This difference becomes more apparent by the end of the second year of long-term follow up.

About the authors

М. М. Burkin

Karelian Research Medical Center of the North-West Branch of the Russian Academy of Medical Sciences, Petrozavodsk State University

Email: shabanov@mail.rcom.ru
Russian Federation, Petrozavodsk

I. Р. Dudanov

Karelian Research Medical Center of the North-West Branch of the Russian Academy of Medical Sciences, Petrozavodsk State University

Email: shabanov@mail.rcom.ru
Russian Federation, Petrozavodsk

V. A. Terevnikov

Karelian Research Medical Center of the North-West Branch of the Russian Academy of Medical Sciences, Petrozavodsk State University

Email: shabanov@mail.rcom.ru
Russian Federation, Petrozavodsk

N. S. Subbotina

Karelian Research Medical Center of the North-West Branch of the Russian Academy of Medical Sciences, Petrozavodsk State University

Email: shabanov@mail.rcom.ru
Russian Federation, Petrozavodsk

I. I. Dudanova

Karelian Research Medical Center of the North-West Branch of the Russian Academy of Medical Sciences, Petrozavodsk State University

Author for correspondence.
Email: shabanov@mail.rcom.ru
Russian Federation, Petrozavodsk

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